Pang Kristine K Y, Chao Nicholas S Y, Tsang T K, Lau Betty Y T, Leung K Y, Ting S H, Leung Michael W Y, Liu Kelvin K W
Division of Paediatric Surgery, Department of Surgery, Queen Elizabeth Hospital, Jordan, Hong Kong.
Department of Radiology and Imaging, Queen Elizabeth Hospital, Jordan, Hong Kong.
Hong Kong Med J. 2015 Feb;21(1):80-3. doi: 10.12809/hkmj133925.
A baby girl presented with an antenatal diagnosis of a retroperitoneal tumour. Postnatal imaging suggested that this mass contained two fetiform structures with spine and long bone formation. This teratomatous mass was completely excised at 3 weeks of age. Histology was consistent with twin fetuses-in-fetu, revealing two fetiform masses each with an umbilical cord connecting to a common placenta-like mass. Despite a difference in the weight of the twin fetuses-in-fetu, the level of organogenesis was identical and corresponded to fetuses of 10 weeks of gestation. Each mass had four limbs, intact skin, rib cage, intestines, anus, ambiguous genitalia, primitive brain tissue and a spine with ganglion cells in the cord. Although considered a mature teratoma in the current World Health Organization classification, the theory of formation from multiple pregnancies has been commonly implied in more recent literature. The true aetiology of this rare condition remains unclear.
一名女婴在产前被诊断出患有腹膜后肿瘤。产后影像学检查显示，该肿块包含两个具有脊柱和长骨形成的胎儿样结构。这个畸胎瘤性肿块在婴儿3周龄时被完全切除。组织学检查结果与胎儿型联体双胎相符，显示两个胎儿样肿块，每个肿块都有一条脐带连接到一个共同的胎盘样肿块。尽管胎儿型联体双胎的体重有所差异，但器官发生水平相同，相当于妊娠10周的胎儿。每个肿块都有四肢、完整的皮肤、胸廓、肠道、肛门、生殖器模糊、原始脑组织以及脊髓中有神经节细胞的脊柱。尽管在世界卫生组织目前的分类中被认为是成熟畸胎瘤，但多胎妊娠形成理论在最近的文献中已被普遍提及。这种罕见病症的真正病因仍不清楚。
