流感病毒血凝素的免疫识别
Immune recognition of influenza virus haemagglutinin.
作者信息
Skehel J J, Barnet B C, Burt D S, Daniels R S, Douglas A R, Graham C M, Hodgson J, Knossow M, Mills K H, Riska P F
机构信息
National Institute for Medical Research, Mill Hill, London, U.K.
出版信息
Philos Trans R Soc Lond B Biol Sci. 1989 Jun 12;323(1217):479-83; discussion 483-5. doi: 10.1098/rstb.1989.0025.
Haemagglutinin glycoproteins are the components of influenza virus membranes against which infectivity-neutralizing antibodies are directed. Sequence analysis of natural and laboratory-selected variant haemagglutinins indicates the regions of the molecule recognized by antibodies and by helper T cells; the identity of these regions and the relations between them are discussed.
血凝素糖蛋白是流感病毒膜的组成成分，感染性中和抗体即针对这些成分。对天然及实验室筛选出的变异型血凝素进行序列分析，可确定抗体及辅助性T细胞识别的分子区域；本文将讨论这些区域的特性及其相互关系。
Zotero 插件