Fetissof F, Arbeille B, Bellet D, Barre I, Lansac J
Laboratoire d'Anatomie pathologique, Faculté de Médecine, Tours, France.
Virchows Arch B Cell Pathol Incl Mol Pathol. 1989;57(2):117-21. doi: 10.1007/BF02899072.
Endocrine cells were investigated in human Bartholin's glands by use of histochemical, immunohistochemical and ultrastructural methods. Endocrine cells represent normal constituents of these glands, being mainly distributed throughout the transitional epithelium of the major excretory duct; however, single elements are dispersed among the acinar lobules. Serotonin-, calcitonin-, katacalcin-, bombesin- and alpha-hCG-immunoreactive cells were recognized, with serotonin-immunoreactive cells predominating. Co-expression of calcitonin, katacalcin or alpha-hCG with serotonin was observed in single endocrine cells. At the ultrastructural level, these cells are richly granulated and show typical neuroendocrine features. Bartholin's glands display an endocrine profile quite similar to that of other cloacal-derived tissues.
采用组织化学、免疫组织化学和超微结构方法对人巴氏腺中的内分泌细胞进行了研究。内分泌细胞是这些腺体的正常组成部分，主要分布在主要排泄管的移行上皮中；然而，单个细胞散在于腺泡小叶之间。识别出了血清素、降钙素、katacalcin、蛙皮素和α - 人绒毛膜促性腺激素免疫反应性细胞，其中血清素免疫反应性细胞占主导。在单个内分泌细胞中观察到降钙素、katacalcin或α - 人绒毛膜促性腺激素与血清素的共表达。在超微结构水平上，这些细胞富含颗粒，并表现出典型的神经内分泌特征。巴氏腺的内分泌特征与其他泄殖腔来源的组织非常相似。
