去铁胺的氘标记同位素异构体的合成。
Synthesis of deuterium-labelled isotopomer of deferasirox.
作者信息
Havaldar Freddy H, Dabholkar Bhushan Vasant, Mule Ganesh Baban, Kulkarni Suhas
机构信息
Nadkarni-Sacasa Research Laboratory, St. Xavier's College, Mumbai, India.
出版信息
J Labelled Comp Radiopharm. 2015 Apr;58(4):163-5. doi: 10.1002/jlcr.3266. Epub 2015 Feb 17.
PMID:25693166
Abstract
A d4 -labeled isotopomer of deferasirox was synthesized as internal standard for use in a LC/mass spectroscopy (MS)/MS method developed for the simultaneous quantitative determination of deferasirox in human serum. d4 -deferasirox was synthesized from d8 -toluene.
摘要
合成了一种d4标记的地拉罗司同位素异构体作为内标，用于开发的液相色谱/质谱（MS）/MS方法，该方法用于同时定量测定人血清中的地拉罗司。d4-地拉罗司由d8-甲苯合成。
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