Peng Na, Wang Kai-Feng, Liu Guo-Guang, Zeng Ling-Ze, Yao Kun, Lu Wen-Ying
Huan Jing Ke Xue. 2014 Oct;35(10):3794-9.
This paper studied the phtodegradation behavior, mechanism and security of propranolol (PRO) in water under ultraviolet irradiation using the high pressure mercury lamp. The photodegradation mechanism was verified by reactive oxygen species (ROS) quenching method, and the photoproducts security was evaluated by luminescent bacteria toxicity test. The results showed that the rate of photolysis (k) of PRO decreased with increasing initial concentration, and showed a significant negative correlation (r2 > 0.95). The increasing k value was also accompanied with higher pH of the solution, and the k values were 0.0953-0.267 min(-1) under pH 5-9. ROS quenching experiments showed that the PRO UV photolysis process included a triplet PRO (3PRO*) direct photolysis participation, and self-sensitized photolysis participation caused by hydroxyl radical (·OH) and singlet oxygen (1O2). Direct photolysis rate was greater than the rate of self-sensitized photolysis. The result of 1O2 steady concentration measured by FFA as the probe was consistent with the quenching method. The toxicity evaluation illustrated the formation of some intermediate photoproducts, which were more toxic than PRO.
本文采用高压汞灯研究了水中普萘洛尔（PRO）在紫外光照射下的光降解行为、机理及安全性。通过活性氧（ROS）猝灭法验证光降解机理，通过发光细菌毒性试验评估光产物的安全性。结果表明，PRO的光解速率（k）随初始浓度的增加而降低，呈显著负相关（r2>0.95）。k值的增加还伴随着溶液pH值的升高，在pH 5-9条件下，k值为0.0953-0.267 min(-1)。ROS猝灭实验表明，PRO的紫外光解过程包括三线态PRO（3PRO*）直接光解参与以及由羟基自由基（·OH）和单线态氧（1O2）引起的自敏化光解参与。直接光解速率大于自敏化光解速率。以FFA为探针测定的1O2稳态浓度结果与猝灭法一致。毒性评价表明形成了一些中间光产物，其毒性比PRO更大。
