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硬膜外类固醇注射后圆锥综合征:病例报告

Conus medullaris syndrome after epidural steroid injection: Case report.

作者信息

Tackla Ryan D, Keller Jeffrey T, Ernst Robert J, Farley Chad W, Bohinski Robert J

机构信息

Department of Neurosurgery, University of Cincinnati Academic Health Center, Cincinnati, OH.

Department of Neurosurgery, University of Cincinnati Academic Health Center, Cincinnati, OH ; Mayfield Clinic, Cincinnati, OH.

出版信息

Int J Spine Surg. 2012 Dec 1;6:29-33. doi: 10.1016/j.ijsp.2011.10.002. eCollection 2012.

Abstract

BACKGROUND

Given the risk of paralysis associated with cervical transforaminal injection, is it time to reconsider transforaminal injections of the lumbar spine? Arguments for discontinuing lumbar injections have been discussed in the anesthesia literature, raising concern about the risks of epidural steroid injections (ESIs).

METHODS

In a 47-year-old man, paraplegia of the lower extremities developed, specifically conus medullaris syndrome, after he underwent an ESI for recurrent pain. Correct needle placement was verified with epidurography. Immediately after the injection, the patient felt his legs "going dead"; paraplegia of the lower extremities was noted.

RESULTS

An initial magnetic resonance imaging study performed after the patient was transferred to the emergency department was unremarkable. However, a later neurosurgical evaluation showed conus medullaris syndrome, and a second magnetic resonance imaging study showed the conus infarct. We conducted a search of the PubMed database of articles from 2002 to 2011 containing the following keywords: complications, lumbar epidural steroid injection(s), cauda equina syndrome, conus medullaris infarction, spinal cord infarction, spinal cord injury, paralysis, paresis, plegia, paresthesia, and anesthesia.

CONCLUSIONS

Summarizing this case and 5 similar cases, we weigh the potential benefits and risks of ESI. Although one can safely assume that this severe, devastating complication is rare, we speculate that its true incidence remains unknown, possibly because of medicolegal implications. We believe that the rarity of this complication should not preclude the continued use of transforaminal ESI; rather, it should be emphasized for discussion with patients during the consent process.

摘要

背景

鉴于颈椎经椎间孔注射存在瘫痪风险,是否到了重新考虑腰椎经椎间孔注射的时候?麻醉学文献中已讨论过停止腰椎注射的理由,这引发了对硬膜外类固醇注射(ESI)风险的担忧。

方法

一名47岁男性在接受ESI治疗复发性疼痛后出现下肢截瘫,具体为圆锥马尾综合征。通过硬膜外造影证实了针头放置正确。注射后患者立即感觉双腿“失去知觉”,随后发现下肢截瘫。

结果

患者转至急诊科后最初进行的磁共振成像检查未见异常。然而,后来的神经外科评估显示为圆锥马尾综合征,第二次磁共振成像检查显示圆锥梗死。我们在PubMed数据库中搜索了2002年至2011年包含以下关键词的文章:并发症、腰椎硬膜外类固醇注射、马尾综合征、圆锥梗死、脊髓梗死、脊髓损伤、瘫痪、轻瘫、截瘫、感觉异常和麻醉。

结论

总结该病例及5例类似病例,我们权衡了ESI的潜在益处和风险。虽然可以安全地假设这种严重的毁灭性并发症很少见,但我们推测其真实发生率仍然未知,可能是由于法医学方面的影响。我们认为这种并发症的罕见性不应妨碍继续使用经椎间孔ESI;相反,在知情同意过程中应向患者强调并进行讨论。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8463/4300874/814461fec05f/IJSS-6-2011-10-002-g001.jpg

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