Departments of *Neurosurgery †Radiology ‡Pathology §Anesthesiology ∥Orthopedic Surgery, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
Clin J Pain. 2013 Dec;29(12):e39-41. doi: 10.1097/AJP.0b013e31829a4cc6.
Clinically significant spinal hemorrhage is an extremely rare but potentially devastating complication of spinal epidural steroid injection. We report a rare case of cauda equina syndrome after spinal epidural injection that inadvertently penetrated an unrecognized spinal paraganglioma.
The clinical records for a patient presenting with cauda equina syndrome were retrospectively reviewed. A literature search was performed to identify reports of cauda equina syndrome in patients undergoing spinal epidural steroid injection, as well as recent large series describing complications associated with these injections.
A 37-year-old man presented to our emergency department with severe low back pain radiating bilaterally to the lower extremities and urinary incontinence. His pain had greatly intensified 1 day after spinal epidural steroid injection. He had a 1-year history of low back pain diagnosed as disk herniation and managed conservatively but had experienced recent onset of a similar pain and new onset of nocturnal back pain causing sleep disturbance. Epidural injection had been administered based on the earlier diagnosis of disk herniation. Examination using magnetic resonance imaging revealed a previously unrecognized oval hemorrhagic mass lesion at L2-3, which had been inadvertently penetrated during epidural injection. Emergent en bloc resection resolved the patient's neurological symptoms. At histopathologic analysis, the tumor was diagnosed as a spinal paraganglioma.
The presented case indicates the importance of a thorough history, physical examination, and imaging assessment before spinal epidural steroid injection.
临床显著的脊柱出血是椎管内硬膜外类固醇注射极为罕见但潜在破坏性的并发症。我们报告一例因椎管内硬膜外注射而无意中穿透未被识别的脊柱副神经节瘤导致马尾综合征的罕见病例。
回顾性审查一位出现马尾综合征的患者的临床记录。进行了文献检索,以确定在接受椎管内硬膜外类固醇注射的患者中出现马尾综合征的报告,以及最近描述这些注射相关并发症的大型系列研究。
一位 37 岁男性因严重腰痛双侧放射至下肢和尿失禁到我院急诊科就诊。他的疼痛在椎管内硬膜外类固醇注射后 1 天急剧加剧。他有 1 年的腰痛病史,被诊断为椎间盘突出症,并接受保守治疗,但最近出现类似疼痛和新出现的夜间背痛导致睡眠障碍。根据先前的椎间盘突出症诊断,进行了硬膜外注射。磁共振成像检查显示 L2-3 处有一个先前未被识别的椭圆形出血性肿块病变,在硬膜外注射过程中无意中穿透。紧急整块切除术解决了患者的神经症状。在组织病理学分析中,该肿瘤被诊断为脊柱副神经节瘤。
所报告的病例表明,在进行椎管内硬膜外类固醇注射之前,进行全面的病史、体格检查和影像学评估非常重要。