Rafful Claudia, Zule William, González-Zúñiga Patricia E, Werb Dan, Medina-Mora María Elena, Magis-Rodriguez Carlos, Strathdee Steffanie A
University of California , San Diego, La Jolla, CA .
Am J Drug Alcohol Abuse. 2015 May;41(3):220-5. doi: 10.3109/00952990.2015.1011742. Epub 2015 Feb 19.
High dead-space syringes (HDSS) are believed to confer an elevated risk of acquiring HIV and other blood-borne infections.
We identified prevalence and correlates of HDSS use among injection drug users (IDU) in Tijuana, Mexico, where syringe purchase and possession is legal without a prescription.
Beginning in 2011, IDU who reported being 18 years or older and injected drugs within the last month were recruited into a prospective study. At baseline and semi-annually, 557 IDU underwent HIV-testing and interviewer-administered surveys. Logistic regression was used to identify correlates of using HDSS.
Of 557 IDU, 40% had ever used HDSS, mostly because no other syringe type was available (72%), or because they were easier to get (20%). Controlling for sex and age at first injection, use of HDSS was associated with cocaine as the first drug injected (Adjusted Odds Ratio [AOR]: 2.68; Confidence Interval 95% [CI]: 1.15-6.22), having been stopped or arrested by police (AOR: 1.84; 95% CI: 1.11-3.07), being deported from the US (AOR: 1.64; 95% CI:1.06-2.53), and believing it is illegal to carry syringes (AOR:1.78; 95% CI: 1.01-3.15).
Use of HDSS is surprisingly common among IDU in Tijuana. Efforts are needed to expand coverage of low-dead space syringes through existing syringe exchange programs. Education is required to increase awareness of the harms associated with HDSS, and to inform IDU that syringe possession is legal across Mexico.
高死腔注射器(HDSS)被认为会增加感染艾滋病毒和其他血源性感染的风险。
我们确定了墨西哥蒂华纳注射吸毒者(IDU)中HDSS的使用情况及其相关因素,在该地无需处方购买和持有注射器是合法的。
从2011年开始,招募报告年龄在18岁及以上且在过去一个月内注射过毒品的IDU参与一项前瞻性研究。在基线和每半年时,557名IDU接受了艾滋病毒检测和访谈式调查。采用逻辑回归来确定使用HDSS的相关因素。
在557名IDU中,40%曾使用过HDSS,主要原因是没有其他类型的注射器(72%),或者因为它们更容易获得(20%)。在控制首次注射时的性别和年龄后,使用HDSS与首次注射的毒品为可卡因有关(调整后的优势比[AOR]:2.68;95%置信区间[CI]:1.15 - 6.22),曾被警察拦下或逮捕(AOR:1.84;95% CI:1.11 - 3.07),被从美国驱逐出境(AOR:1.64;95% CI:1.06 - 2.53),以及认为携带注射器是非法的(AOR:1.78;95% CI:1.01 - 3.15)。
在蒂华纳的IDU中,HDSS的使用出人意料地普遍。需要通过现有的注射器交换项目扩大低死腔注射器的覆盖范围。需要开展教育,以提高对与HDSS相关危害的认识,并告知IDU在墨西哥持有注射器是合法的。