Isozumi Rie, Uemura Haruki, Kimata Isao, Ichinose Yoshio, Logedi John, Omar Ahmeddin H, Kaneko Akira
Emerg Infect Dis. 2015 Mar;21(3):490-2. doi: 10.3201/eid2103.140898.
We looked for mutations in the Plasmodium falciparum K13 propeller gene of an artemisinin-resistant parasite on islands in Lake Victoria, Kenya, where transmission in 2012-2013 was high. The 4 new types of nonsynonymous, and 5 of synonymous, mutations we detected among 539 samples analyzed provide clues to understanding artemisinin-resistant parasites.
我们在肯尼亚维多利亚湖岛屿上对一株青蒿素抗性疟原虫的恶性疟原虫K13螺旋桨基因进行了突变检测，该地区在2012 - 2013年期间疟疾传播率很高。在分析的539个样本中，我们检测到4种新型非同义突变和5种同义突变，这些突变为理解青蒿素抗性疟原虫提供了线索。
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