From the Departments of Anesthesiology and Public Health Sciences, University of Rochester School of Medicine, Rochester, New York; RAND Health, RAND, Boston, Massachusetts; F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland; School of Public Health, University at Albany, State University of New York, Albany, New York; Department of Anesthesiology and Critical Care, University of Pennsylvania Health System, Philadelphia, Pennsylvania; and Anesthesia Quality Institute, Park Ridge, Illinois.
Anesth Analg. 2015 Mar;120(3):526-533. doi: 10.1213/ANE.0000000000000522.
One of every 150 hospitalized patients experiences a lethal adverse event; nearly half of these events involves surgical patients. Although variations in surgeon performance and quality have been reported in the literature, less is known about the influence of anesthesiologists on outcomes after major surgery. Our goal of this study was to determine whether there is significant variation in outcomes between anesthesiologists after controlling for patient case mix and hospital quality.
Using clinical data from the New York State Cardiac Surgery Reporting System, we conducted a retrospective observational study of 7920 patients undergoing isolated coronary artery bypass graft surgery. Multivariable logistic regression modeling was used to examine the variation in death or major complications (Q-wave myocardial infarction, renal failure, stroke) across anesthesiologists, controlling for patient demographics, severity of disease, comorbidities, and hospital quality.
Anesthesiologist performance was quantified using fixed-effects modeling. The variability across anesthesiologists was highly significant (P < 0.001). Patients managed by low-performance anesthesiologists (corresponding to the 25th percentile of the distribution of anesthesiologist risk-adjusted outcomes) experienced nearly twice the rate of death or serious complications (adjusted rate 3.33%; 95% confidence interval [CI], 3.09%-3.58%) as patients managed by high-performance anesthesiologists (corresponding to the 75th percentile) (adjusted rate 1.82%; 95% CI, 1.58%-2.10%). This performance gap was observed across all patient risk groups.
The rate of death or major complications among patients undergoing coronary artery bypass graft surgery varies markedly across anesthesiologists. These findings suggest that there may be opportunities to improve perioperative management to improve outcomes among high-risk surgical patients.
每 150 名住院患者中就有 1 人会经历致命的不良事件;其中近一半的事件涉及手术患者。尽管文献中已经报道了外科医生绩效和质量的差异,但对于麻醉师对大手术后结果的影响知之甚少。我们这项研究的目的是确定在控制患者病例组合和医院质量的情况下,麻醉师之间的结果是否存在显著差异。
我们使用来自纽约州心脏手术报告系统的临床数据,对 7920 例行单纯冠状动脉旁路移植术的患者进行了回顾性观察性研究。使用多变量逻辑回归模型,在控制患者人口统计学、疾病严重程度、合并症和医院质量的情况下,检查麻醉师之间死亡或主要并发症(Q 波心肌梗死、肾衰竭、中风)的差异。
使用固定效应模型量化了麻醉师的绩效。麻醉师之间的差异具有高度显著性(P < 0.001)。由低绩效麻醉师管理的患者(对应于麻醉师风险调整结果分布的第 25 个百分位数)经历死亡或严重并发症的发生率几乎是高绩效麻醉师管理的患者(对应于第 75 个百分位数)的两倍(调整后的发生率为 3.33%;95%置信区间[CI],3.09%-3.58%)(调整后的发生率为 1.82%;95%CI,1.58%-2.10%)。这种绩效差距在所有患者风险组中都存在。
接受冠状动脉旁路移植术的患者的死亡或主要并发症发生率在麻醉师之间差异显著。这些发现表明,可能有机会改善围手术期管理,以改善高风险手术患者的预后。