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[极低出生体重新生儿的红细胞输血]

[Red blood cell transfusions in very low birth weight newborns].

作者信息

Folatre B Isabel, Kuschel B Carla, Marín H Francisco

出版信息

Rev Chil Pediatr. 2014 Jun;85(3):298-303. doi: 10.4067/S0370-41062014000300005.

DOI:10.4067/S0370-41062014000300005
PMID:25697246
Abstract

INTRODUCTION

It has been reported that 80% of very low birth weight infants (VLBWI) are receiving packed red blood cell transfusions (PRBCtr), and in 90% of cases, the indication is the replacement of the blood collected. The existence of guidelines for transfusion practices has had a great impact on the decline in the number of transfusions. The aim of this paper is to describe the characteristics of VLBW infants who are packed red blood cell transfusion receptors.

PATIENTS AND METHODS

This is a descriptive cross-sectional study, which included the medical records of all VLBW newborns older than 72 hours, released from the Neonatology department of the Hospital Valdivia Base, between 2005 and 2006. Birth weight, gestational age, pulmonary surfactant, hyaline membrane, mechanical ventilation, bronchopulmonary dysplasia, sepsis and packed red blood cell transfusions were evaluated. Guidelines for packed red cell transfusions were used at the Hospital.

RESULTS

93 newborns were evaluated and 62 of them were transfused (66.7%); they received 2.1 ± 0.9 PRBC transfusion and the exposure to different donors was 2.1 ± 0.9. The VLBW infants susceptible to be PRBCtr receptor were those younger than 30 weeks' gestational age, weighing less than 1,250 g and with respiratory failure, mechanical ventilation and sepsis.

CONCLUSION

The observed percentages of transfused infants with very low birth weight, median PRBCtr and exposure to different donors can be attributed to the existence of guidelines for neonatal transfusion practices and a team of highly experienced neonatologists.

摘要

引言

据报道,80%的极低出生体重儿(VLBWI)接受了红细胞悬液输注(PRBCtr),且在90%的病例中,输注指征是补充采集的血液。输血实践指南的存在对输血次数的减少产生了重大影响。本文旨在描述接受红细胞悬液输注的极低出生体重儿的特征。

患者与方法

这是一项描述性横断面研究,纳入了2005年至2006年期间从瓦尔迪维亚基地医院新生儿科出院的所有年龄超过72小时的极低出生体重新生儿的病历。评估了出生体重、胎龄、肺表面活性物质、透明膜病、机械通气、支气管肺发育不良、败血症和红细胞悬液输注情况。该医院采用了红细胞悬液输注指南。

结果

共评估了93例新生儿,其中62例接受了输血(66.7%);他们接受了2.1±0.9次红细胞悬液输注,接触不同献血者的次数为2.1±0.9次。易成为红细胞悬液输注受体的极低出生体重儿为胎龄小于30周、体重小于1250g且患有呼吸衰竭、机械通气和败血症的婴儿。

结论

观察到的极低出生体重输血婴儿的百分比、红细胞悬液输注中位数以及接触不同献血者的情况可归因于新生儿输血实践指南的存在以及一组经验丰富的新生儿科医生。

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