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[素食母亲的婴儿因维生素B12缺乏导致血液学和神经学损害:病例报告]

[Hematological and neurological compromise due to vitamin B12 deficit in infant of a vegetarian mother: case report].

作者信息

Bravo J Paulina, Ibarra C Judith, Paredes M Marcela

出版信息

Rev Chil Pediatr. 2014 Jun;85(3):337-43. doi: 10.4067/S0370-41062014000300010.

Abstract

INTRODUCTION

Vitamin B12 deficiency is extremely common in strict vegetarians and their variants. Infants of vegetarian mothers have a higher risk of deficiency and are more prone to its effects.

OBJECTIVE

To report a case in order to warn people about the importance of suspected vitamin B12 deficiency in children of vegetarian mothers.

CASE REPORT

A 12-month old infant, daughter of a longtime vegetarian woman, who presented neurological and hematological compromise due to vitamin B12 deficiency, is discussed. After a short period of parenteral administration of cyanocobalamin and enteral nutrition, the patient evolved with clinical and laboratory improvement, although she still had residual development delay.

CONCLUSIONS

Vitamin B12 deficiency is often not suspected by the pediatrician in healthy infants. Clinical manifestations can be nonspecific, such as apathy, food refusal and progressive impairment of psychomotor development. A nutritional anamnesis performed on the mother (with great emphasis on those strict vegetarians) to estimate her reserves in the period prior to, during and after delivery can be critical to detect the risk of this vitamin deficiency in young children.

摘要

引言

维生素B12缺乏在严格素食者及其变体人群中极为常见。素食母亲的婴儿缺乏维生素B12的风险更高,且更容易受到其影响。

目的

报告一例病例,以警示人们关注素食母亲的孩子疑似维生素B12缺乏的重要性。

病例报告

讨论了一名12个月大的婴儿,其母亲长期素食,该婴儿因维生素B12缺乏出现神经和血液系统损害。在短期胃肠外给予氰钴胺和肠内营养后,患者病情好转,临床和实验室指标改善,尽管仍有残留的发育迟缓。

结论

健康婴儿的维生素B12缺乏往往未被儿科医生怀疑。临床表现可能不具特异性,如冷漠、拒食和精神运动发育逐渐受损。对母亲进行营养问诊(尤其着重于那些严格素食者),以评估其在分娩前、分娩期间和分娩后的储备情况,对于检测幼儿维生素缺乏风险可能至关重要。

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