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瑞典西部因心脏骤停接受冠状动脉造影的患者的血管造影结果与生存率

Angiographic findings and survival in patients undergoing coronary angiography due to sudden cardiac arrest in western Sweden.

作者信息

Redfors Björn, Råmunddal Truls, Angerås Oskar, Dworeck Christian, Haraldsson Inger, Ioanes Dan, Petursson P, Libungan Berglind, Odenstedt Jacob, Stewart Jason, Robertsson Lotta, Wahlin Magnus, Albertsson Per, Herlitz Johan, Omerovic Elmir

机构信息

Department of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden.

Department of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden.

出版信息

Resuscitation. 2015 May;90:13-20. doi: 10.1016/j.resuscitation.2014.11.034. Epub 2015 Feb 16.

Abstract

AIM

Sudden cardiac arrest (SCA) accounts for more than half of all deaths from coronary heart disease. Time to return of spontaneous circulation is the most important determinant of outcome but successful resuscitation also requires percutaneous coronary intervention in selected patients. However, proper selection of patients is difficult. We describe data on angiographic finding and survival from a prospectively followed SCA patient cohort.

METHODS

We merged the RIKS-HIA registry (Register of Information and Knowledge about Swedish Heart Intensive Care Admissions) and SCAAR (Swedish Coronary Angiography and Angioplasty Registry) for patients hospitalized in cardiac care units in Western Sweden between January 2005 and March 2013. We performed propensity score-adjusted logistic and Cox proportional-hazards regression analyses on complete-case data as well as on imputed data sets.

RESULTS

638 consecutive patients underwent coronary angiography due to SCA. Severity of coronary artery disease was similar among SCA patients and patients undergoing coronary angiography due to suspected coronary artery disease (n=37,142). An acute occlusion was reported in the majority of SCA patients and was present in 37% of patients who did not have ST-elevation on the post resuscitation ECG. 31% of SCA patients died within 30 days. Long-term risk of death among patients who survived the first 30 days was higher in patients with SCA compared to patients with acute coronary syndromes (P<0.001).

CONCLUSIONS

Coronary artery disease and acute coronary occlusions are common among patients who undergo coronary angiography after sudden cardiac arrest. These patients have a substantial mortality risk both short- and long-term.

摘要

目的

心脏骤停(SCA)占冠心病所致所有死亡的一半以上。自主循环恢复时间是预后的最重要决定因素,但成功复苏还需要对部分患者进行经皮冠状动脉介入治疗。然而,患者的恰当选择很困难。我们描述了一个前瞻性随访的SCA患者队列的血管造影结果和生存数据。

方法

我们合并了2005年1月至2013年3月期间在瑞典西部心脏监护病房住院患者的RIKS-HIA注册库(瑞典心脏重症监护入院信息与知识注册库)和SCAAR(瑞典冠状动脉造影和血管成形术注册库)。我们对完整病例数据以及插补数据集进行倾向评分调整的逻辑回归和Cox比例风险回归分析。

结果

638例连续的因SCA接受冠状动脉造影的患者。SCA患者与因疑似冠状动脉疾病接受冠状动脉造影的患者(n = 37,142)的冠状动脉疾病严重程度相似。大多数SCA患者报告有急性闭塞,且在复苏后心电图无ST段抬高的患者中,37%存在急性闭塞。31%的SCA患者在30天内死亡。与急性冠状动脉综合征患者相比,SCA存活患者在最初30天存活后的长期死亡风险更高(P<0.001)。

结论

冠状动脉疾病和急性冠状动脉闭塞在心脏骤停后接受冠状动脉造影的患者中很常见。这些患者短期和长期均有较高的死亡风险。

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