McMillan A, Bishop P E, Aw D, Peutherer J F
Department of Medicine, University of Edinburgh, UK.
AIDS. 1989 May;3(5):309-12. doi: 10.1097/00002030-198905000-00011.
An immunohistological study of the rash associated with acute HIV infection in a homosexual man was undertaken. The salient feature was an infiltrate of mononuclear cells predominantly of the CD4+ phenotype around the superficial dermal vessels. HIV p24 antigen was detected in occasional cells, possibly Langerhans' cells, of the infiltrate. Their presentation of HIV antigen to local CD4+ cells may lead to a delayed type hypersensitivity reaction.
对一名同性恋男性急性HIV感染相关皮疹进行了免疫组织学研究。显著特征是浅表真皮血管周围主要为CD4 +表型的单核细胞浸润。在浸润细胞中偶尔检测到HIV p24抗原，这些细胞可能是朗格汉斯细胞。它们将HIV抗原呈递给局部CD4 +细胞可能会导致迟发型超敏反应。
