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Mucosal-associated invariant T cells in inflammatory bowel diseases: bystanders, defenders, or offenders?

作者信息

Treiner Emmanuel

机构信息

Centre de Physiopathologie de Toulouse-Purpan (CPTP) INSERM UMR1043 , Toulouse , France.

出版信息

Front Immunol. 2015 Feb 2;6:27. doi: 10.3389/fimmu.2015.00027. eCollection 2015.

DOI:10.3389/fimmu.2015.00027
PMID:25699045
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4313715/
Abstract
摘要

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本文引用的文献

1
Mucosal-associated invariant T-cells: new players in anti-bacterial immunity.黏膜相关恒定 T 细胞：抗细菌免疫的新成员。
Front Immunol. 2014 Oct 8;5:450. doi: 10.3389/fimmu.2014.00450. eCollection 2014.
2
Toll-like receptor 8 agonist and bacteria trigger potent activation of innate immune cells in human liver.Toll样受体8激动剂与细菌可触发人肝脏中固有免疫细胞的强效激活。
PLoS Pathog. 2014 Jun 26;10(6):e1004210. doi: 10.1371/journal.ppat.1004210. eCollection 2014 Jun.
3
Innate mucosal-associated invariant T (MAIT) cells are activated in inflammatory bowel diseases.先天黏膜相关恒定 T（MAIT）细胞在炎症性肠病中被激活。
Clin Exp Immunol. 2014 May;176(2):266-74. doi: 10.1111/cei.12277.
4
CD161++ CD8+ T cells, including the MAIT cell subset, are specifically activated by IL-12+IL-18 in a TCR-independent manner.CD161++ CD8+ T 细胞，包括 MAIT 细胞亚群，可通过非 TCR 依赖性方式被 IL-12+IL-18 特异性激活。
Eur J Immunol. 2014 Jan;44(1):195-203. doi: 10.1002/eji.201343509. Epub 2013 Oct 1.
5
Recognition of vitamin B metabolites by mucosal-associated invariant T cells.黏膜相关恒定 T 细胞识别维生素 B 代谢物。
Nat Commun. 2013;4:2142. doi: 10.1038/ncomms3142.
6
Increased levels of circulating Th17 cells in quiescent versus active Crohn's disease.静止期 versus 活动期克罗恩病患者循环 Th17 细胞水平升高。
J Crohns Colitis. 2013 Apr;7(3):248-55. doi: 10.1016/j.crohns.2012.06.015. Epub 2012 Jul 10.
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Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial.司库奇尤单抗，一种人源抗白细胞介素-17A 单克隆抗体，用于中重度克罗恩病：一项随机、双盲、安慰剂对照试验的意外结果。
Gut. 2012 Dec;61(12):1693-700. doi: 10.1136/gutjnl-2011-301668. Epub 2012 May 17.
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Proinflammatory cytokines in the pathogenesis of inflammatory bowel diseases.促炎细胞因子在炎症性肠病发病机制中的作用。
Gastroenterology. 2011 May;140(6):1756-1767. doi: 10.1053/j.gastro.2011.02.016.
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Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17-secreting T cells.人类 MAIT 细胞是对异源物有抗性的、组织靶向的、CD161hi 白细胞介素-17 分泌的 T 细胞。
Blood. 2011 Jan 27;117(4):1250-9. doi: 10.1182/blood-2010-08-303339. Epub 2010 Nov 17.
10
The dual nature of T(H)17 cells: shifting the focus to function.T(H)17 细胞的双重性质：将焦点转移到功能上。
Nat Immunol. 2010 Jun;11(6):471-6. doi: 10.1038/ni.1882. Epub 2010 May 18.