Stanasel Irina, Le Hoang-Kim, Bilgutay Aylin, Roth David R, Gonzales Edmond T, Janzen Nicolette, Koh Chester J, Gargollo Patricio, Seth Abhishek
Scott Department of Urology, Baylor College of Medicine and Texas Children's Hospital, Houston, and Scott and White Healthcare, Temple, Texas.
Scott Department of Urology, Baylor College of Medicine and Texas Children's Hospital, Houston, and Scott and White Healthcare, Temple, Texas.
J Urol. 2015 Aug;194(2):512-6. doi: 10.1016/j.juro.2015.02.044. Epub 2015 Feb 17.
Proximal hypospadias repair using a staged approach is a complex reconstructive operation with the potential for significant complications requiring repeat surgery. We report outcomes of staged hypospadias repair using transposed preputial skin flaps and factors predictive of postoperative complications.
We retrospectively analyzed patients who underwent staged proximal hypospadias repair using transposed preputial skin flaps between 2002 and 2013. Patient demographics, operative details, complications, reoperations and factors predictive of complications were reviewed.
A total of 56 patients were identified with a mean age of 14.1 months (median 14.3) at first stage. Mean followup was 38.6 months (median 34.1). Complications requiring additional unplanned operation(s) were observed in 38 patients (68%), including fistulas in 32 (57%), diverticula in 8 (14%), meatal stenosis in 5 (9%), urethral stricture in 8 (14%) and glans dehiscence in 3 (5%). In addition, redo first stage repair was performed in 4 patients (7%). Since some patients had more than 1 complication, the total number of complications is greater than the number of patients undergoing a redo operation. On univariate analyses the use of small intestinal submucosa was significantly associated with an increased risk of fistula (91% vs 49%, p = 0.02) and urethral diverticulum (64% vs 24%, p = 0.04). Incision of the tunica albuginea of the corpora was associated with an increased likelihood of fistula (77% vs 44%, p = 0.03). Finally, patients with glans dehiscence were significantly younger at first stage (5.8 vs 14.8 months, p = 0.01).
The reoperation rate for complications in children undergoing staged hypospadias repair using transposed preputial skin flaps is higher than previously reported.
采用分期手术修复近端尿道下裂是一种复杂的重建手术,有可能出现严重并发症,需要再次手术。我们报告了使用转位包皮皮瓣分期修复尿道下裂的结果以及术后并发症的预测因素。
我们回顾性分析了2002年至2013年间接受转位包皮皮瓣分期修复近端尿道下裂的患者。回顾了患者的人口统计学资料、手术细节、并发症、再次手术情况以及并发症的预测因素。
共确定56例患者,第一期手术时的平均年龄为14.1个月(中位数14.3个月)。平均随访时间为38.6个月(中位数34.1个月)。38例患者(68%)出现需要额外进行计划外手术的并发症,包括32例瘘管(57%)、8例憩室(14%)、5例尿道口狭窄(9%)、8例尿道狭窄(14%)和3例龟头裂开(5%)。此外,4例患者(7%)进行了一期修复的再次手术。由于部分患者有不止一种并发症,并发症总数多于接受再次手术的患者数量。单因素分析显示,使用小肠黏膜下层与瘘管风险增加(91%对49%,p = 0.02)和尿道憩室风险增加(64%对24%,p = 0.04)显著相关。白膜切开与瘘管发生可能性增加相关(77%对44%,p = 0.03)。最后,出现龟头裂开的患者在第一期手术时年龄显著更小(5.8个月对14.8个月,p = 0.01)。
采用转位包皮皮瓣分期修复尿道下裂的儿童并发症再次手术率高于先前报道。