Department of Urology, Shanghai Children's Hospital, School of medicine, Shanghai Jiao Tong University, Shanghai, 200040, China.
World J Urol. 2023 Mar;41(3):813-819. doi: 10.1007/s00345-023-04296-0. Epub 2023 Feb 6.
This study aimed to compare the efficacy of modified transverse preputial island flap (TPIF) repair with the traditional TPIF procedure and Byar's two-stage procedure in proximal hypospadias repair, especially in the postoperative urethral stricture incidence rates.
Patients admitted for proximal hypospadias treated with modified TPIF repair, the traditional TPIF procedure, or Byar's two-stage procedure at our institution from 2017 to 2021 were identified, and the incidence of postoperative complications among them was compared.
In total, 142 patients were included (modified TPIF group, 43; traditional TPIF group, 37; and Byar's two-stage group, 62). The length of the neourethra was 4.21 ± 0.63 cm in the modified TPIF group, 4.18 ± 0.71 cm in the traditional TPIF group, and 4.20 ± 0.68 cm in the Byar's two-stage group. The rate of urethral stricture in the modified TPIF group (two cases, 4.65%) was significantly lower than that in the traditional TPIF group (four cases, 10.81%) (P = 0.008). Seven (16.28%) cases of urethrocutaneous fistula occurred in the modified TPIF group, six (16.22%) in the traditional TPIF group, and eight (12.90%) in the two-stage group. Additionally, one case (2.33%) of urethral diverticulum occurred in the modified TPIF group, one (2.70%) in the traditional TPIF group, and three (4.84%) in Byar's two-stage group.
Modified TPIF repair can ensure a wedge anastomosis between the proximal urethral meatus and the neourethra, provide support and blood supply for the neourethra. Furthermore, it extended the urethral plate width at the anastomosis and urethral meatus, effectively reducing the incidence of urethral strictures.
本研究旨在比较改良横形包皮岛状瓣(TPIF)修复与传统 TPIF 术式和 Byar 两阶段术式在近端尿道下裂修复中的疗效,尤其是在术后尿道狭窄发生率方面。
回顾性分析 2017 年至 2021 年期间在我院接受改良 TPIF 修复、传统 TPIF 术式或 Byar 两阶段术式治疗的近端尿道下裂患者,比较术后并发症发生率。
共纳入 142 例患者(改良 TPIF 组 43 例,传统 TPIF 组 37 例,Byar 两阶段组 62 例)。改良 TPIF 组新尿道长度为 4.21±0.63cm,传统 TPIF 组为 4.18±0.71cm,Byar 两阶段组为 4.20±0.68cm。改良 TPIF 组尿道狭窄发生率(2 例,4.65%)明显低于传统 TPIF 组(4 例,10.81%)(P=0.008)。改良 TPIF 组发生尿道瘘 7 例(16.28%),传统 TPIF 组 6 例(16.22%),两阶段组 8 例(12.90%)。此外,改良 TPIF 组发生尿道憩室 1 例(2.33%),传统 TPIF 组 1 例(2.70%),两阶段组 3 例(4.84%)。
改良 TPIF 修复可保证近段尿道外口与新尿道的楔形吻合,为新尿道提供支撑和血供,同时延长吻合口及尿道外口处的尿道板宽度,有效降低尿道狭窄发生率。