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[内镜逆行胰胆管造影术后十二指肠穿孔]

[Duodenal perforations after endoscopic retrograde cholangiopancreatography].

作者信息

Armas Ojeda María Desirée, Ojeda Marrero Vanesa, Roque Castellano Cristina, Cabrera Marrero José Carlos, Mathías Gutierrez María Del Pino, Ceballos Santos Daniel, Marchena Gómez Joaquín

机构信息

Servicio de Cirugía General y del Aparato Digestivo, Hospital Universitario de Gran Canaria Doctor Negrín, Las Palmas de Gran Canaria, España.

Servicio de Digestivo, Hospital Universitario de Gran Canaria Doctor Negrín, Las Palmas de Gran Canaria, España.

出版信息

Cir Esp. 2015 Jun-Jul;93(6):403-10. doi: 10.1016/j.ciresp.2015.01.004. Epub 2015 Feb 19.

Abstract

INTRODUCTION

Duodenal perforations after endoscopic retrograde cholangiopancreatography (ERCP) are an uncommon complication. The management of this kind of perforation is controversial. The aim of this study was to analyze the results of the management of a series of 15 patients who were diagnosed with this complication.

METHODS

Retrospective study of duodenal perforations after ERCP diagnosed at a tertiary level hospital, between 2001 and 2011. The variables age, sex, ERCP indication, type of perforation, time of diagnosis, clinical presentation, radiographic findings, management, surgical technique, length of stay and intrahospital mortality were recorded and analyzed.

RESULTS

Out of a total of 1923 ERCP performed, 15 duodenal perforations were detected (0,78%). Perforation site was the duodenal wall (3 cases) and periampullary (12 cases). Eleven perforations were suspected during the procedure. Patients with duodenal wall perforations underwent immediate surgery. Seven of 12 periampullary perforations were managed conservatively with a favorable outcome in 5 of them. Subsequent scheduled surgery was performed in 4 cases. The mean length of hospital stay was 21,2 days (range: 3-49) and intra-hospital mortality was 20%.

CONCLUSIONS

Perforations after ERCP have high mortality rates, and require a complicated therapeutic approach that needs to be individualized. Selective conservative management is a valid and safe option in selected patients.

摘要

引言

内镜逆行胰胆管造影术(ERCP)后十二指肠穿孔是一种罕见的并发症。这类穿孔的处理存在争议。本研究的目的是分析一系列15例诊断为此类并发症患者的处理结果。

方法

对2001年至2011年在一家三级医院诊断的ERCP术后十二指肠穿孔进行回顾性研究。记录并分析年龄、性别、ERCP适应证、穿孔类型、诊断时间、临床表现、影像学检查结果、处理方式、手术技术、住院时间和院内死亡率等变量。

结果

在总共进行的1923例ERCP中,检测到15例十二指肠穿孔(0.78%)。穿孔部位为十二指肠壁(3例)和壶腹周围(12例)。11例穿孔在操作过程中被怀疑。十二指肠壁穿孔的患者立即接受手术。12例壶腹周围穿孔中有7例采用保守治疗,其中5例预后良好。4例随后进行了择期手术。平均住院时间为21.2天(范围:3 - 49天),院内死亡率为20%。

结论

ERCP术后穿孔死亡率高,需要复杂的个体化治疗方法。在特定患者中,选择性保守治疗是一种有效且安全的选择。

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