泮托拉唑对初治2型糖尿病患者胰岛素分泌的影响。
Effect of pantoprazole on insulin secretion in drug-naïve patients with type 2 diabetes.
作者信息
González-Ortiz Manuel, Martínez-Abundis Esperanza, Mercado-Sesma Arieh R, Álvarez-Carrillo Rebeca
机构信息
Institute of Experimental and Clinical Therapeutics, Physiology Department, Health Science University Center, University of Guadalajara, Guadalajara, Mexico; Medical Research Unit in Clinical Epidemiology, Specialties Hospital, Medical Unit of High Specialty, West National Medical Center, Mexican Institute of Social Security, Guadalajara, Mexico.
Institute of Experimental and Clinical Therapeutics, Physiology Department, Health Science University Center, University of Guadalajara, Guadalajara, Mexico.
出版信息
Diabetes Res Clin Pract. 2015 Apr;108(1):e11-3. doi: 10.1016/j.diabres.2015.01.039. Epub 2015 Feb 7.
To evaluate the effect of pantoprazole during 45 days on insulin secretion in drug-naïve patients with type 2 diabetes, a randomized, double blind, placebo control clinical trial was performed in 14 drug-naïve volunteers. Significant increases in late insulin phase and total insulin secretion, and decreases in HbA1c levels were found.
为评估泮托拉唑在45天内对初治2型糖尿病患者胰岛素分泌的影响，对14名初治志愿者进行了一项随机、双盲、安慰剂对照临床试验。结果发现晚期胰岛素分泌阶段和总胰岛素分泌显著增加，糖化血红蛋白水平降低。
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