Cojocaru Inimioara Mihaela, Cojocaru Manole, Silosi Isabela, Vrabie Camelia Doina
Clinic of Neurology, Colentina Clinical Hospital, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
Discipline of Physiology, "Dr. Ion Stoia" Clinical Center for Rheumatic Diseases, Faculty of Medicine, "Titu Maiorescu" University, Bucharest, Romania.
Maedica (Bucur). 2014 Sep;9(3):289-94.
The peripheral nervous system refers to parts of the nervous system outside the brain and spinal cord. Systemic autoimmune diseases can affect both the central and peripheral nervous systems in a myriad of ways and through a heterogeneous number of mechanisms leading to many different clinical manifestations. As a result, neurological complications of these disorders can result in significant morbidity and mortality. The most common complication of peripheral nervous system (PNS) involvement is peripheral neuropathy, with symptoms of numbness, sensory paresthesias, weakness, or gait imbalance. The neuropathy may be multifocal and asymmetric or, less frequently, distal and symmetric.
周围神经系统是指脑和脊髓以外的神经系统部分。系统性自身免疫性疾病可通过多种机制以多种方式影响中枢和周围神经系统，导致许多不同的临床表现。因此，这些疾病的神经并发症可导致显著的发病率和死亡率。周围神经系统（PNS）受累最常见的并发症是周围神经病变，症状包括麻木、感觉异常、无力或步态失衡。神经病变可能是多灶性和不对称的，或者较少见的是远端和对称的。
