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Effect of full flavor and denicotinized cigarettes exposure on the brain microvascular endothelium: a microarray-based gene expression study using a human immortalized BBB endothelial cell line.全味和去尼古丁香烟暴露对脑微血管内皮的影响:一项基于微阵列的基因表达研究,使用人永生化血脑屏障内皮细胞系。
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本文引用的文献

1
Cigarette smoking and variations in systemic immune and inflammation markers.吸烟与全身免疫及炎症标志物的变化
J Natl Cancer Inst. 2014 Oct 1;106(11). doi: 10.1093/jnci/dju294. Print 2014 Nov.
2
Oxidative and pro-inflammatory impact of regular and denicotinized cigarettes on blood brain barrier endothelial cells: is smoking reduced or nicotine-free products really safe?常规香烟和去尼古丁香烟对血脑屏障内皮细胞的氧化和促炎作用:吸烟减少或无尼古丁产品真的安全吗?
BMC Neurosci. 2014 Apr 23;15:51. doi: 10.1186/1471-2202-15-51.
3
Smoking and cardiovascular disease: mechanisms of endothelial dysfunction and early atherogenesis.吸烟与心血管疾病:内皮功能障碍与早期动脉粥样硬化形成的机制。
Arterioscler Thromb Vasc Biol. 2014 Mar;34(3):509-15. doi: 10.1161/ATVBAHA.113.300156.
4
Blood-brain barrier structure and function and the challenges for CNS drug delivery.血脑屏障的结构和功能以及中枢神经系统药物递送的挑战。
J Inherit Metab Dis. 2013 May;36(3):437-49. doi: 10.1007/s10545-013-9608-0. Epub 2013 Apr 23.
5
Cigarette smoke and inflammation: role in cerebral aneurysm formation and rupture.香烟烟雾与炎症:在颅内动脉瘤形成和破裂中的作用。
Mediators Inflamm. 2012;2012:271582. doi: 10.1155/2012/271582. Epub 2012 Dec 13.
6
Smoking as a risk factor for multiple sclerosis.吸烟是多发性硬化症的一个危险因素。
Mult Scler. 2013 Jul;19(8):1022-7. doi: 10.1177/1352458512470862. Epub 2012 Dec 20.
7
Tight junctions at the blood brain barrier: physiological architecture and disease-associated dysregulation.血脑屏障的紧密连接:生理结构和与疾病相关的失调。
Fluids Barriers CNS. 2012 Nov 9;9(1):23. doi: 10.1186/2045-8118-9-23.
8
Pathophysiological impact of cigarette smoke exposure on the cerebrovascular system with a focus on the blood-brain barrier: expanding the awareness of smoking toxicity in an underappreciated area.香烟烟雾暴露对脑血管系统的病理生理学影响,重点关注血脑屏障:在一个未被充分认识的领域提高对吸烟毒性的认识。
Int J Environ Res Public Health. 2010 Dec;7(12):4111-26. doi: 10.3390/ijerph7124111. Epub 2010 Nov 26.
9
Nicotine aggravates the brain postischemic inflammatory response.尼古丁加剧脑缺血后炎症反应。
Am J Physiol Heart Circ Physiol. 2011 Apr;300(4):H1518-29. doi: 10.1152/ajpheart.00928.2010. Epub 2011 Jan 14.
10
Nicotine exacerbates brain edema during in vitro and in vivo focal ischemic conditions.尼古丁在体外和体内局灶性缺血情况下加重脑水肿。
J Pharmacol Exp Ther. 2010 Feb;332(2):371-9. doi: 10.1124/jpet.109.157776. Epub 2009 Nov 4.

Differential Cerebrovascular Toxicity of Various Tobacco Products: A Regulatory Perspective.

作者信息

Sajja Ravi K, Naik Pooja, Cucullo Luca

机构信息

Department of Pharmaceutical Sciences, Texas Tech University Health Sciences Center, Amarillo, USA.

出版信息

J Pharmacovigil. 2015;3(1). doi: 10.4172/2329-6887.1000e130.

DOI:10.4172/2329-6887.1000e130
PMID:25705706
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4334139/
Abstract
摘要