Chain B M, Mitchison N A, Mitchison T J, Davies D H, Marcinkiewicz J
Department of Biology, University College London, UK.
J Autoimmun. 1989 Jun;2 Suppl:45-53. doi: 10.1016/0896-8411(89)90116-9.
A dogmatic view of antigen processing is presented in outline, followed by a survey of unresolved issues in the subject. The activity of Thy 1 as an alloantigen, and allospecific MHC Class-II-restricted cytolytic T cells offer examples of exceptional cases of antigen presentation. Implications for the design of vaccines are drawn.
本文概述了对抗原加工的教条式观点，随后调查了该主题中尚未解决的问题。Thy 1作为同种异体抗原的活性以及同种特异性MHC II类限制性细胞溶解T细胞提供了抗原呈递特殊情况的例子。并阐述了对疫苗设计的启示。
