Kronlage Steven C, Menendez Mariano E
The Andrews Institute, Gulf Breeze, FL; Hand and Upper Extremity Service, Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, MA.
The Andrews Institute, Gulf Breeze, FL; Hand and Upper Extremity Service, Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, MA.
J Hand Surg Am. 2015 Mar;40(3):438-44.e1. doi: 10.1016/j.jhsa.2014.12.012.
To compare change in numbness and pain after carpal tunnel release in patients with electrophysiologically moderate and severe disease.
We tested the primary null hypothesis that there is no difference in the total Carpal Tunnel Symptoms Scale score 3 months after surgery between patients with moderate and those with severe disease. Ninety-five patients (47 in the moderate cohort, and 48 in the severe cohort) who had miniopen carpal tunnel release between November 2011 and November 2013 were identified from our prospectively collected database. For each patient, the total Carpal Tunnel Symptoms Scale score, as well the numbness and pain subscale scores, at the preoperative and postoperative (2-wk, 1-mo, 2-mo, 3-mo, ≥ 1-y) visits were documented. The data were analyzed with repeated-measures analysis of variance.
Three months after surgery, patients with moderate carpal tunnel syndrome (CTS) reported, on average, no symptoms, and patients with severe disease had reduced but unresolved symptoms. Although symptoms diminished in both groups from the preoperative assessment to the 2-week postoperative assessment, patients with severe CTS had comparatively more severe symptoms at all time points with the exception of pain at 2 weeks and 1 year or longer after surgery, at which times there was no significant difference. At 1 year or longer after surgery, 1 (2%) patient with moderate CTS and 9 (19%) patients with severe CTS reported continued symptoms. Preoperative electrodiagnostic severity was the factor most predictive of symptom scores.
Patients with severe CTS experience considerable reduction in symptoms after surgery but should be informed that recovery may be more prolonged and, in some cases, incomplete 1 year after carpal tunnel release, particularly with regard to numbness.
TYPE OF STUDY/LEVEL OF EVIDENCE: Prognostic III.
比较电生理检查为中度和重度疾病的患者在腕管松解术后麻木和疼痛的变化。
我们检验了主要无效假设,即中度和重度疾病患者术后3个月的腕管综合征症状量表总分无差异。从我们前瞻性收集的数据库中确定了95例在2011年11月至2013年11月期间接受小切口腕管松解术的患者(中度组47例,重度组48例)。记录每位患者术前及术后(2周、1个月、2个月、3个月、≥1年)访视时的腕管综合征症状量表总分以及麻木和疼痛子量表得分。采用重复测量方差分析对数据进行分析。
术后3个月,中度腕管综合征(CTS)患者平均报告无症状,重度疾病患者症状减轻但未消除。虽然两组患者从术前评估到术后2周评估症状均有所减轻,但除术后2周以及1年或更长时间的疼痛外,重度CTS患者在所有时间点的症状相对更严重,而在这些时间点两组无显著差异。术后1年或更长时间,1例(2%)中度CTS患者和9例(19%)重度CTS患者报告仍有症状。术前电诊断严重程度是症状评分最具预测性的因素。
重度CTS患者术后症状有显著减轻,但应告知他们恢复可能会更漫长,在某些情况下,腕管松解术后1年恢复不完全,尤其是在麻木方面。
研究类型/证据水平:预后性研究III级