Duckworth Andrew D, Jenkins Paul J, Roddam Philip, Watts Adam C, Ring David, McEachan Jane E
Department of Orthopaedic Surgery, Queen Margaret Hospital, Dunfermline, Fife, UK.
J Hand Surg Am. 2013 Aug;38(8):1540-6. doi: 10.1016/j.jhsa.2013.05.027.
Pain is not a classical symptom of carpal tunnel syndrome (CTS), with the exception of numbness that is so intense that it is described by patients as painful. The primary aim of our study was to determine which factors correlated with pain for patients diagnosed with CTS.
We prospectively assessed all patients diagnosed with CTS in our unit over a 1-year period. We recorded demographic details for all patients, including past medical history, body mass index, smoking, and occupation. The diagnosis and severity of carpal tunnel syndrome were established through a combination of history, clinical assessment, and nerve conduction studies. Of 275 patients diagnosed and treated for CTS, 183 were women (67%), the mean age was 55 years (range, 22-87 y), and 166 cases were bilateral (60%). The mean body mass index was 29.5 kg/m2 (range, 17-48 kg/m2), and 81 patients smoked (30%). Patients completed a Short Form-McGill pain questionnaire (SF-MPQ) as a measure of pain at initial presentation. We assessed outcome 1 year after intervention using the Quick Disabilities of the Arm, Shoulder, and Hand (QuickDASH) score.
We found no association between pain according to the SF-MPQ and the positive clinical signs of CTS or positive nerve conduction studies. Multivariate analysis demonstrated that smoking and bilateral disease independently correlated with the overall SF-MPQ, with similar findings on subanalysis. Independent factors associated with an increased improvement in the QuickDASH at 1 year were the presentation QuickDASH score, positive nerve conduction studies, and smoking.
The only independent factors that correlated with pain at presentation of CTS were smoking and bilateral disease. Pain according to the SF-MPQ was not associated with classical clinical findings of the disease or with positive findings on nerve conduction testing.
TYPE OF STUDY/LEVEL OF EVIDENCE: Prognostic I.
疼痛并非腕管综合征(CTS)的典型症状,除了麻木感强烈到患者将其描述为疼痛的情况。我们研究的主要目的是确定哪些因素与被诊断为CTS的患者的疼痛相关。
我们对本单位在1年期间内所有被诊断为CTS的患者进行了前瞻性评估。我们记录了所有患者的人口统计学细节,包括既往病史、体重指数、吸烟情况和职业。通过病史、临床评估和神经传导研究相结合的方式确定腕管综合征的诊断和严重程度。在275例被诊断并接受治疗的CTS患者中,183例为女性(67%),平均年龄为55岁(范围22 - 87岁),166例为双侧病例(60%)。平均体重指数为29.5 kg/m²(范围17 - 48 kg/m²),81例患者吸烟(30%)。患者在初次就诊时完成了简短麦吉尔疼痛问卷(SF - MPQ)以评估疼痛程度。我们在干预1年后使用手臂、肩部和手部快速残疾评定量表(QuickDASH)评分评估结果。
我们发现根据SF - MPQ得出的疼痛与CTS的阳性临床体征或阳性神经传导研究之间没有关联。多因素分析表明,吸烟和双侧疾病与总体SF - MPQ独立相关,亚分析结果相似。与1年后QuickDASH改善增加相关的独立因素是初次就诊时的QuickDASH评分、阳性神经传导研究和吸烟。
与CTS就诊时疼痛相关的唯一独立因素是吸烟和双侧疾病。根据SF - MPQ得出的疼痛与该疾病的经典临床发现或神经传导测试的阳性结果无关。
研究类型/证据水平:预后性研究I级