氯氮卓中毒合并肝性脑病患者持续静脉输注氟马西尼
Continuous intravenous flumazenil infusion in a patient with chlordiazepoxide toxicity and hepatic encephalopathy.
作者信息
Al-Halawani Moh'd, Sen Parijat, Abdeen Yazan, Shaaban Hamid, Klukowicz Allan J, Miller Richard A
机构信息
Department of Internal Medicine, Saint Michael's Medical Center, Newark, New Jersey, USA.
Department of Pulmonary, Saint Michael's Medical Center, Newark, New Jersey, USA.
出版信息
J Emerg Trauma Shock. 2015 Jan-Mar;8(1):58-60. doi: 10.4103/0974-2700.145422.
Abstract
Flumazenil, a benzodiazepine receptor antagonist, is the drug of choice for the diagnosis and treatment of benzodiazepine overdose. We are presenting a patient with chronic alcoholism and alcoholic liver disease, who came with alcohol withdrawal symptoms and treated chlordiazepoxide. Subsequently he developed a prolonged change in mental status that required treatment for benzodiazepine overdose and hepatic encephalopathy with flumazenil infusion for 28 days.
摘要
氟马西尼是一种苯二氮䓬受体拮抗剂，是诊断和治疗苯二氮䓬过量的首选药物。我们报告一例患有慢性酒精中毒和酒精性肝病的患者，该患者出现酒精戒断症状并接受了氯氮䓬治疗。随后，他出现了精神状态的长期改变，需要用氟马西尼输注治疗苯二氮䓬过量和肝性脑病，持续了28天。
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