Kruchinina O V, Gal'perina E I, Shepoval'nikov A N
Fiziol Cheloveka. 2014 Sep-Oct;40(5):14-21.
Adolescence is characterized by an intensive formation of inter-regional cortical fields interaction, in this period significantly reorganized the activities of deep brain structures and cortical-subcortical interaction are enhanced. Our objectives were to evaluate the nature of changes in the spatial organization of brain bioelectric potentials with age and characteristics of such an organization in adolescents. For this purpose, EEG studies have been conducted in 230 subjects of both sexes aged 4 to 35 years. We estimated interdependent changes of biopotentials correlations fluctuations in 20-lead EEG, using the integral index Vol. Analyzed age-related changes of EEG correlations in rest condition and during verbal activity (Russian and English texts audition). Verbal tasks were sued in subjects over 8 years. It was found that the spatial synchronization of the EEG both in background and verbal activity increases with age, but after 20 years the rate of change is significantly reduced. In adolescence (12-17 years old), sex differences appear between the degree of EEG coherence processes occurring in the left and right hemispheres in subjects performing verbal tasks. In males 12 to 14 years nonlinear changes in overall correlation (indicators VOL) was observed, whereas in females of this age systemic reorganization of the brain interrelations occurs more smoothly, ahead of 1.5-2 years.
青春期的特点是区域间皮质区域相互作用的密集形成，在此期间，深部脑结构的活动显著重组，皮质-皮质下相互作用增强。我们的目标是评估脑生物电势空间组织随年龄变化的性质以及青少年这种组织的特征。为此，对230名年龄在4至35岁的男女受试者进行了脑电图研究。我们使用积分指数Vol估计了20导联脑电图中生物电势相关性波动的相互依存变化。分析了静息状态和言语活动（听俄语和英语文本）期间脑电图相关性的年龄相关变化。8岁以上的受试者进行了言语任务。结果发现，脑电图在背景和言语活动中的空间同步性随年龄增加，但20岁后变化速率显著降低。在青春期（12至17岁），执行言语任务的受试者左右半球脑电图相干过程的程度存在性别差异。12至14岁的男性观察到整体相关性（指标VOL）的非线性变化，而这个年龄段的女性大脑相互关系的系统性重组发生得更平稳，提前1.5至2年。
