Galvis Virgilio, Tello Alejandro, Jaramillo Luis C, Paredes David, Camacho Paul A
Department of Ophthalmology, Centro Oftalmológico Virgilio Galvis, Floridablanca, Santander, Colombia ; Universidad Autónoma de Bucaramanga, Bucaramanga, Santander, Colombia.
Universidad Autónoma de Bucaramanga, Bucaramanga, Santander, Colombia ; Fundación Oftalmológica de Santander (FOSCAL), Floridablanca, Santander, Colombia.
Open Ophthalmol J. 2015 Jan 30;9:12-6. doi: 10.2174/1874364101509010012. eCollection 2015.
To perform a prevalence study of Punctate Keratopathy of West Indians in Colombian individuals and to propose a new name for the condition.
Prospective, population-based epidemiological study. All patients evaluated between November 1 and December 31, 2012, in the Centro Oftalmológico Virgilio Galvis and Fundación Oftalmológica de Santander (FOSCAL), Floridablanca, Colombia, with clinical findings of white corneal opacities corresponding to Punctate Keratopathy of West Indians were identified. Careful slit-lamp examination was performed for clinical diagnosis and findings were reported in the electronic medical record indicating number and location of the lesions. Prevalence was calculated for the total population, and for gender and age groups. Furthermore a literature review was performed and a new name for the condition proposed.
In the whole group of patients, prevalence was 1.0%. No one case was diagnosed in a patient younger than 21 year-old. No one lesion was located within 2.5 mm of the corneal apex. 96% of affected patients had unilateral involvement. 58.5% of eyes had a single corneal lesion; 7% of eyes had 6 or 7 corneal lesions.
The condition heretofore known as Punctate Keratopathy of West Indians was present in 1% of our patients in Colombia (South America). Thus, this non-infectious, non-inflammatory, asymptomatic ailment of unknown etiology is not restricted to people of Antillean descent, or who have lived in these islands. We propose the new name "Rice's keratopathy". Age and male gender were independent risk factors for the presence of the keratopathy.
对哥伦比亚人群中具有西印度人点状角膜病变特征的患者进行患病率研究，并为该病症提出一个新名称。
基于人群的前瞻性流行病学研究。对2012年11月1日至12月31日期间在哥伦比亚弗洛里达布兰卡的维吉尔·加尔维斯眼科中心和桑坦德眼科基金会（FOSCAL）接受评估、临床检查发现有符合西印度人点状角膜病变特征的白色角膜混浊的所有患者进行识别。通过仔细的裂隙灯检查进行临床诊断，并将检查结果记录在电子病历中，注明病变的数量和位置。计算总人群以及不同性别和年龄组的患病率。此外，进行了文献综述并为该病症提出一个新名称。
在整个患者组中，患病率为1.0%。未在21岁以下患者中诊断出任何病例。没有一个病变位于角膜顶点2.5毫米范围内。96%的受影响患者为单侧受累。58.5%的眼睛有单个角膜病变；7%的眼睛有6或7个角膜病变。
迄今为止被称为西印度人点状角膜病变的病症在我们哥伦比亚（南美洲）的患者中占1%。因此，这种病因不明的非感染性、非炎症性、无症状疾病并不局限于安的列斯群岛后裔或曾在这些岛屿生活过的人。我们提议将其新命名为“赖斯角膜病变”。年龄和男性性别是角膜病变存在的独立危险因素。
