Gad El-Hak N, Mostafa M, Hamdy E, Haleem M
Hepatogastroenterology. 2014 Oct;61(135):1961-70.
Gastroesophageal reflux disease (GERD) is a common upper GIT disorder. The choice of surgical management options is debatable between laparoscopic Nissen fundoplication (LNF) and Toupet fundoplication (LTF) especially in cases with esophageal dysmotility. PATIENTS AND METHODS/AIMS: 102 patients with chronic GERD divided into 2 groups. Group (1): Patients with good peristalsis (n=70) done LNF. Group (2): Patients with poor peristalsis (n=32) patients done LTF to compare the outcome. They were included in this study. They subjected to clinical, radiological and esophageal motility investigations.
In postoperative period, Recurrent of heartburn, dysphagia and abdominal distension were found in 5.71% , 14.28% and 27.14% post LNF and in 9.37%, 15.62% and 15.62% post LTF respectively. Pre operative LESP was 10.16±5.4 mmHg in LNF & 9.56±3.51 mmHg in LTF group increased to 20.7±7.84 mmHg early after LNF (p<0.0001) & 15.26±6.47 early after LTF (p = 0.0002). Esophageal 24hrs pH metry in early and late post operative showed a significant improvement of % reflux (p < 0.001) in both groups.
Toupet fundoplication became the procedure of choice of cases with esophageal dysmotility due to its ease of application, patient satisfaction, low dysphagia rate and low levels of abdominal distension.
胃食管反流病(GERD)是一种常见的上消化道疾病。在腹腔镜下Nissen胃底折叠术(LNF)和Toupet胃底折叠术(LTF)之间,手术治疗方案的选择存在争议,尤其是在食管动力障碍的病例中。
患者与方法/目的:102例慢性GERD患者分为两组。第1组:蠕动良好的患者(n = 70)接受LNF。第2组:蠕动不良的患者(n = 32)接受LTF,以比较疗效。他们被纳入本研究。对他们进行了临床、放射学和食管动力检查。
术后,LNF术后烧心、吞咽困难和腹胀的复发率分别为5.71%、14.28%和27.14%,LTF术后分别为9.37%、15.62%和15.62%。术前LNF组LES压力为10.16±5.4 mmHg,LTF组为9.56±3.51 mmHg,LNF术后早期升至20.7±7.84 mmHg(p < 0.0001),LTF术后早期升至15.26±6.47 mmHg(p = 0.0002)。术后早期和晚期的食管24小时pH监测显示两组的反流百分比均有显著改善(p < 0.001)。
由于Toupet胃底折叠术应用简便、患者满意度高、吞咽困难发生率低且腹胀程度低,已成为食管动力障碍病例的首选手术方式。