Giarola A
Arch Ital Urol Nefrol Androl. 1989 Sep;61(3):297-306.
It is more than 25 years that several Authors stress the need of an early treatment of undescended testis both mono or bilateral. The pathogenesis of undescended testis is still unknown, but some suggestions about the hormonal role has been formulated. From these considerations "interregional groups to study the cryptorchidism" has been formed, in order to use the same parameters of evaluation: auxologic studies, cytogenetic analysis, hormonal tests, dynamic hypophyseal functionality test, medical treatment, surgical treatment, biopsies, postoperative hormonal treatment, seminal evaluation after 20 years of life. From all these studies a protocol has been planned, including a treatment by HCG associated with urophollitropine as pure FSH stimulating effect and an eventual surgical treatment before the 5th years of life.
25年多来,多位作者强调了对单侧或双侧隐睾进行早期治疗的必要性。隐睾的发病机制仍不清楚,但已提出了一些关于激素作用的观点。基于这些考虑,成立了“研究隐睾症的区域间小组”,以便采用相同的评估参数:体格学研究、细胞遗传学分析、激素检测、垂体动态功能检测、药物治疗、手术治疗、活检、术后激素治疗、20岁后的精液评估。通过所有这些研究制定了一个方案,包括用与人绒毛膜促性腺激素联合的尿促性素进行治疗,因为其具有纯促卵泡生成素刺激作用,以及在5岁前进行最终的手术治疗。