Derizhanova I S, Semashkevich L M, Matsionis A E, Shakunov A N
Vopr Onkol. 1989;35(8):956-61.
Clinico-anatomical analysis was performed in 13 cases of endocrine tumors of various sites with concomitant gastric and duodenal ulcer (Zollinger-Ellison's syndrome). Ulcer tended to recur in these patients; it was associated with pronounced pain and involved a high rate of such complications as perforation, bleeding and gastrointestinal fistula. Endocrine tumors were found to locate in the pancreas (5) and duodenum (5) while, in the other three patients, multiple endocrine adenomatosis (type 1) was identified. Correct diagnosis was made in three cases only and surgery was successful in two of them. Errors are analysed.
对13例伴有胃和十二指肠溃疡(佐林格 - 埃利森综合征)的不同部位内分泌肿瘤患者进行了临床解剖学分析。这些患者的溃疡易于复发;伴有明显疼痛,且穿孔、出血和胃肠瘘等并发症发生率较高。发现内分泌肿瘤位于胰腺(5例)和十二指肠(5例),另外3例患者确诊为多发性内分泌腺瘤病1型。仅3例确诊,其中2例手术成功。对误诊情况进行了分析。