[Effect of nootropic agents on the brain bioelectrical activity and on the indices of neuromediator metabolism in the acute period of severe craniocerebral trauma].

Clinico-biochemical examination and EEG were conducted in 39 patients with severe craniocerebral trauma who were given nootropic agents in a complex of intensive therapy measures. Four types of changes of monoamine metabolism in treatment with piracetam were revealed which were combined with two types of EEG changes. The authors recommend the time for beginning piracetam therapy depending on the level of traumatic injury to the brain.