Nesbitt Cassie, Amukotuwa Shalini, Chapman Caron, Batchelor Peter
Department of Neurology, Barwon Health, Barwon Heads, Victoria, Australia.
Department of Radiology, Barwon Health, Geelong, Victoria, Australia.
BMJ Case Rep. 2015 Feb 26;2015:bcr2014206933. doi: 10.1136/bcr-2014-206933.
Epidural blood patching (EBP) is an important therapeutic approach in managing spontaneous cerebrospinal fluid leaks. The mechanism of action of blood patching is likely to be twofold; fluid replacement having an immediate tamponade effect and the proximal flow of blood products having a 'plug' effect. The negative pressure gradient within the epidural space may be important to the rostral flow of injected blood and is possibly increased in intracranial hypotension.
硬膜外血贴疗法(EBP)是治疗自发性脑脊液漏的一种重要方法。血贴的作用机制可能有两方面;液体补充具有即刻的填塞作用,而血液制品的向头端流动具有“堵塞”作用。硬膜外间隙内的负压梯度可能对注入血液的向头端流动很重要,并且在颅内低压时可能会增加。