Nasrallah MacLean P, Nasrallah Ilya M, Yu Gordon H
Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.
Diagn Cytopathol. 2015 May;43(5):427-31. doi: 10.1002/dc.23261. Epub 2015 Feb 26.
Myxoid neurofibromas are benign spindle cell tumors of perineural cell origin with a broad pathologic differential diagnosis, which includes myxoma, myxoid liposarcoma, myxoid dermatofibrosarcoma protuberans, and low-grade fibromyxoid sarcoma. We present an unusual case of superficial myxoid neurofibroma in the region of the breast that underwent pre-operative fine-needle aspiration (FNA). The differential diagnosis for a myxoid subcutaneous lesion should include myxoid neurofibroma when myxoid material is encountered in an otherwise hypocellular FNA.
黏液样神经纤维瘤是起源于神经周围细胞的良性梭形细胞瘤,其病理鉴别诊断范围广泛,包括黏液瘤、黏液样脂肪肉瘤、黏液样隆突性皮肤纤维肉瘤和低度纤维黏液样肉瘤。我们报告了1例发生于乳腺区域的浅表黏液样神经纤维瘤的罕见病例,该病例接受了术前细针穿刺抽吸活检(FNA)。当在细胞成分较少的FNA中发现黏液样物质时,黏液样皮下病变的鉴别诊断应包括黏液样神经纤维瘤。