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25岁女性乳腺黏液样脂肪肉瘤:细针穿刺细胞学诊断中的陷阱——1例罕见病例报告

Myxoid liposarcoma of the breast in a 25-year-old female as a diagnostic pitfall in fine needle aspiration cytology: report of a rare case.

作者信息

Pant Ishita, Kaur Gurjeet, Joshi Sanjeev Chandra, Khalid Imran Abdul

机构信息

Department of Pathology, Advanced Medical and Dental Institute, Malaysia.

出版信息

Diagn Cytopathol. 2008 Sep;36(9):674-7. doi: 10.1002/dc.20913.

Abstract

Primary sarcomas of the breast are extremely rare comprising less than 1.0% of all malignant tumors of the breast. It is even rarer to be reported in a 25-year-old female. This can cause a diagnostic dilemma not only for the clinician but also for the cytopathologist. A 25-year-old woman presented with a well defined firm, mobile lump in her right breast. With fine needle aspiration cytology (FNAC) and ultrasonography a diagnosis of fibroadenoma was made. The patient underwent lumpectomy. Histopathologically it was diagnosed as myxoid liposarcoma. This case is reported to highlight the fact that, even though rare in young females but the possibility of a breast lump being a myxoid liposarcoma does exist. This report discusses a primary myxoid liposarcoma of female breast, considers cytologic differential diagnoses with review of the relevant literature.

摘要

原发性乳腺肉瘤极为罕见,占所有乳腺恶性肿瘤的比例不到1.0%。在一名25岁女性中报道更为罕见。这不仅会给临床医生带来诊断难题,也会给细胞病理学家带来诊断难题。一名25岁女性右乳出现一个边界清晰、质地坚硬、可移动的肿块。通过细针穿刺细胞学检查(FNAC)和超声检查诊断为纤维腺瘤。患者接受了肿块切除术。组织病理学诊断为黏液样脂肪肉瘤。报道该病例是为了强调这样一个事实,即尽管在年轻女性中罕见,但乳腺肿块为黏液样脂肪肉瘤的可能性确实存在。本报告讨论了女性乳腺原发性黏液样脂肪肉瘤,结合相关文献回顾考虑了细胞学鉴别诊断。

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