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比较Versajet™水刀手术与小儿浅度烧伤传统清创术的前瞻性随机对照试验。

Prospective, randomised controlled trial comparing Versajet™ hydrosurgery and conventional debridement of partial thickness paediatric burns.

作者信息

Hyland Ela J, D'Cruz Rachel, Menon Seema, Chan Queenie, Harvey John G, Lawrence Torey, La Hei Erik, Holland Andrew J A

机构信息

The Children's Hospital at Westmead Burns Research Institute, The Children's Hospital at Westmead, Cnr Hawkesbury Rd and Hainsworth St, Westmead, NSW 2145, Australia.

The Children's Hospital at Westmead Burns Research Institute, The Children's Hospital at Westmead, Cnr Hawkesbury Rd and Hainsworth St, Westmead, NSW 2145, Australia.

出版信息

Burns. 2015 Jun;41(4):700-7. doi: 10.1016/j.burns.2015.02.001. Epub 2015 Feb 25.

Abstract

INTRODUCTION

Conventional surgical debridement of burn wounds consists of tangential excision of eschar using a knife or dermabrasion until viable dermis or punctate bleeding occurs. The Versajet™ (Smith and Nephew, St. Petersburg, FL, USA) hydrosurgery system has also been advocated for burn wound debridement, with the suggestion that enhanced preservation of dermal tissue might reduce subsequent scarring.

METHODS

A prospective randomised controlled trial was undertaken comparing Versajet™ to conventional debridement. After excluding those with facial burns, 61 children ≤16 years of age undergoing debridement and skin grafting for partial thickness burns were recruited. Adequacy of debridement was assessed by 2mm punch biopsies taken pre- and post-debridement. Surgical time, percentage graft take at day 10, time to healing, post-operative infection and scarring at 3 and 6 months were assessed.

RESULTS

Thirty-one children underwent conventional debridement and 30 debridement using Versajet™. There was a significant difference in the amount of viable dermal preservation between the two groups (p=0.02), with more viable tissue lost in the conventional group (median 325 μm) versus the Versajet™ group (median 35 μm). There was no significant difference between graft take at day 10 (p=0.9), post-operative wound infection (p=0.5), duration of surgery (p=0.6) or time to healing after grafting (p=0.6). Despite better dermal preservation in the Versajet™ group, there was no significant difference between scarring at 3 or 6 months (p=1.0, 0.1).

CONCLUSIONS

These findings suggest that Versajet™ hydrosurgery appears a more precise method of burn wound debridement. Although dermal preservation may be a factor in reducing subsequent hypertrophic scarring, there were no significant differences found between scarring at 3 or 6 months after-injury.

摘要

引言

传统的烧伤创面手术清创包括用刀进行焦痂的削痂或磨皮,直至出现有活力的真皮或点状出血。Versajet™(美国佛罗里达州圣彼得斯堡的施乐辉公司)水刀手术系统也被推荐用于烧伤创面清创,有人认为增强真皮组织的保留可能会减少后续瘢痕形成。

方法

进行了一项前瞻性随机对照试验,比较Versajet™与传统清创术。排除面部烧伤患者后,招募了61名16岁及以下因浅Ⅱ度烧伤接受清创和植皮手术的儿童。通过清创前后取2mm的钻孔活检来评估清创的充分性。评估手术时间、术后第10天的植皮成活率、愈合时间、术后感染情况以及伤后3个月和6个月时的瘢痕形成情况。

结果

31名儿童接受了传统清创术,30名儿童接受了Versajet™清创术。两组之间在有活力真皮保留量上存在显著差异(p = 0.02),传统组(中位数325μm)比Versajet™组(中位数35μm)损失了更多有活力的组织。术后第10天的植皮成活率(p = 0.9)、术后伤口感染情况(p = 0.5)、手术时长(p = 0.6)或植皮后的愈合时间(p = 0.6)之间均无显著差异。尽管Versajet™组的真皮保留情况更好,但伤后3个月和6个月时的瘢痕形成情况之间无显著差异(p = 1.0,0.1)。

结论

这些研究结果表明,Versajet™水刀手术似乎是一种更精确的烧伤创面清创方法。虽然真皮保留可能是减少后续增生性瘢痕形成的一个因素,但伤后3个月和6个月时的瘢痕形成情况之间未发现显著差异。

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