Ortega-Porcayo Luis Alberto, Ponce-Gómez Juan Antonio, Martínez-Moreno Mauricio, Portocarrero-Ortíz Lesly, Tena-Suck Martha Lilia, Gómez-Amador Juan Luis
Department of Neurosurgery. National Institute of Neurology and Neurosurgery "Manuel Velasco Suarez" Mexico City, Mexico.
Department of Neuroendocrinology. National Institute of Neurology and Neurosurgery "Manuel Velasco Suarez", Mexico City, Mexico.
Int J Surg Case Rep. 2015;9:57-60. doi: 10.1016/j.ijscr.2014.12.038. Epub 2015 Jan 8.
Primary ectopic craniopharyngiomas have only rarely been reported. Craniopharyngiomas involve usually the sellar and suprasellar region, but can be originated from cell remnants of the obliterated craniopharyngeal duct or metaplastic change of andenohypophyseal cells. We present the first case of a primary ectopic frontotemporal craniopharyngioma.
A 35-year old woman presented with a one-year history of headache and diplopia. MRI showed a large frontotemporal cystic lesion. Tumor resection was performed with a keyhole endoscopic frontal lateral approach. The pathological features showed an adamantinomatous craniopharyngioma with a cholesterol granuloma reaction.
There have been reported different localizations for primary ectopic craniopharyngioma. Our case presented a lobulated frontotemporal cystic mass formed by a dense eosinophilic proteinaceous material dystrophic calcifications and cholesterol crystals, with epithelial remnants. No tumor regrowth was observed in the magnetic resonance image 27 months postoperatively.
Primary ectopic craniopharyngioma is a rare entity with a pathogenesis that remains uncertain. This is an unusual anatomic location associated with unique clinical findings.
原发性异位颅咽管瘤仅有极少的报道。颅咽管瘤通常累及鞍区和鞍上区，但可起源于闭塞的颅咽管的细胞残余或腺垂体细胞的化生改变。我们报告首例原发性异位额颞部颅咽管瘤病例。
一名35岁女性，有一年头痛和复视病史。磁共振成像（MRI）显示额颞部有一个大的囊性病变。采用锁孔内镜额外侧入路进行肿瘤切除。病理特征显示为成釉细胞瘤型颅咽管瘤伴胆固醇肉芽肿反应。
原发性异位颅咽管瘤有不同的定位报道。我们的病例表现为一个分叶状的额颞部囊性肿物，由致密的嗜酸性蛋白物质、营养不良性钙化和胆固醇结晶以及上皮残余物构成。术后27个月的磁共振图像未观察到肿瘤复发。
原发性异位颅咽管瘤是一种罕见的疾病，其发病机制尚不确定。这是一个与独特临床表现相关的不寻常解剖位置。
