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再版:急性 A 型主动脉夹层伴血肿的早期和晚期结果。

Reprint of: Early and late outcomes of acute type A aortic dissection with intramural hematoma.

机构信息

Department of Cardiothoracic and Vascular Surgery, Clinical Science Program, The University of Texas Medical School at Houston, and Memorial Hermann Hospital, Houston, Tex.

Department of Cardiothoracic and Vascular Surgery, Clinical Science Program, The University of Texas Medical School at Houston, and Memorial Hermann Hospital, Houston, Tex.

出版信息

J Thorac Cardiovasc Surg. 2015 Feb;149(2 Suppl):S110-5. doi: 10.1016/j.jtcvs.2014.12.036.

Abstract

INTRODUCTION

Controversy remains regarding management of acute type A dissection with intramural hematoma (IMH). Our purpose was to analyze our experience and report outcomes after repair of acute type A aortic dissection with IMH.

METHODS

We analyzed all patients from a single center who underwent open repair for acute type A aortic dissection with IMH.

RESULTS

Between 2000 and 2013, we performed 418 repairs for acute type A aortic dissection. These were divided into 2 groups of patients: 64 patients (15%) with type A IMH and 354 patients (85%) with typical dissection. Those with IMH were older (62.4 ± 13.9 years vs 56.7 ± 14.7 years; P < .0046) and presented with reduced renal function (ie, glomerular filtration rate) (P < .0341), less frequently with distal malperfusion, and less frequently with rupture (P < .0116). With IMH, the time from presentation to repair was, by strategy, longer (median, 67 vs 6 hours; P < .0001), but no mortality occurred within 3 days of presentation. Mortality with IMH did not differ from typical dissection: 7 out of 64 patients (10.9%) versus 52 out of 354 patients (14.7%; P = .4276). A lower incidence of postoperative dialysis in the IMH group approached significance: 6 out of 63 patients (9.5%) versus 64 out of 347 patients (18.4%; P = .0820). When adjusted for age and renal function, late survival was improved with IMH (P < .0343).

CONCLUSIONS

Repair of acute type A aortic dissection with IMH is associated with significant early morbidity and mortality, differing minimally from typical aortic dissection. Although expectant repair within 3 days may be applied, the purposeful delay imparted little advantage. Improved late outcomes may be seen with IMH, but continued long-term surveillance is required for verification.

摘要

简介

对于伴壁内血肿(IMH)的急性 A 型夹层的处理仍存在争议。我们的目的是分析我们的经验,并报告伴 IMH 的急性 A 型主动脉夹层修复后的结果。

方法

我们分析了单中心接受急性 A 型主动脉夹层伴 IMH 开放修复的所有患者。

结果

在 2000 年至 2013 年间,我们对 418 例急性 A 型主动脉夹层患者进行了修复。这些患者分为两组:64 例(15%)伴 A 型 IMH,354 例(85%)伴典型夹层。伴 IMH 的患者年龄更大(62.4 ± 13.9 岁比 56.7 ± 14.7 岁;P<0.0046),肾功能(即肾小球滤过率)降低(P<0.0341),远端灌注不良和破裂较少(P<0.0116)。伴 IMH 时,从发病到手术的时间(策略)较长(中位数,67 比 6 小时;P<0.0001),但在发病后 3 天内无死亡发生。伴 IMH 的死亡率与典型夹层无差异:64 例患者中有 7 例(10.9%),354 例患者中有 52 例(14.7%)(P=0.4276)。伴 IMH 的术后透析发生率较低但未达到显著差异:63 例患者中有 6 例(9.5%),347 例患者中有 64 例(18.4%)(P=0.0820)。在调整年龄和肾功能后,伴 IMH 的晚期生存率提高(P<0.0343)。

结论

伴 IMH 的急性 A 型主动脉夹层修复与显著的早期发病率和死亡率相关,与典型主动脉夹层差异极小。尽管可能应用发病后 3 天内的保守治疗,但故意延迟并没有带来明显的优势。伴 IMH 可能会出现更好的晚期结果,但需要长期监测以验证。

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