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病态肥胖患者围手术期麻醉管理中的争议:我是一名外科医生,为何要关心?

Controversies in perioperative anesthetic management of the morbidly obese: I am a surgeon, why should I care?

作者信息

Sinha Ashish C, Singh Preet Mohinder

机构信息

Anesthesiology and Perioperative Medicine, Drexel University College of Medicine, Philadelphia, PA, USA,

出版信息

Obes Surg. 2015 May;25(5):879-87. doi: 10.1007/s11695-015-1635-5.

Abstract

Over the last four decades, as the rates of obesity have increased, so have the challenges associated with its anesthetic management. In the present review, we discuss perioperative anesthesia management issues that are modifiable by the early involvement of the surgical team. We sum up available evidence or expert opinion on issues like patient positioning, postoperative analgesia, and the effect of continuous positive airway pressure (CPAP) ventilation on surgical anastomosis. We also address established predictors of higher perioperative risk and suggest possible management strategies and concerns of obese patients undergoing same day procedures. Finally, a generalized pharmacological model relevant to altered pharmacokinetics in these patients is presented.

摘要

在过去的四十年里,随着肥胖率的上升,与肥胖麻醉管理相关的挑战也在增加。在本综述中,我们讨论了可通过手术团队早期介入来改变的围手术期麻醉管理问题。我们总结了关于患者体位、术后镇痛以及持续气道正压通气(CPAP)对手术吻合口影响等问题的现有证据或专家意见。我们还阐述了围手术期高风险的既定预测因素,并提出了同日手术肥胖患者可能的管理策略及注意事项。最后,给出了一个与这些患者药代动力学改变相关的通用药理学模型。

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