Scaglione Marco, Ebrille Elisa, Caponi Domenico, Siboldi Alessandra, Bertero Giovanni, Di Donna Paolo, Gabbarini Fulvio, Raimondo Cristina, Di Clemente Francesca, Ferrato Paolo, Marasini Maurizio, Gaita Fiorenzo
Cardiology Division, Cardinal G. Massaia Hospital, Asti, Italy.
Cardiology Division, Department of Medical Sciences, Città della Salute e della Scienza, University of Turin, Turin, Italy.
Pacing Clin Electrophysiol. 2015 Jun;38(6):675-81. doi: 10.1111/pace.12619. Epub 2015 Apr 15.
Fluoroscopic catheter ablation of cardiac arrhythmias in pediatric patients exposes the patients to the potential risk of radiation considering the sensitivity of this population and its longer life expectancy. We evaluated the feasibility, safety, and efficacy of accessory pathway (AP) ablation guided by CARTO3 electroanatomic mapping (EAM) system with both cryoenergy and radiofrequency (RF) energy in order to avoid x-ray exposure in pediatric patients.
We included 44 patients (mean age: 13.1 ± 3.3 years); nine of 44 presented concealed AP. An electrophysiological study with a three-dimensional EAM reconstruction was performed in every patient with a venous transfemoral direct right atrium approach or an arterial transfemoral retrograde approach to reach the mitral annulus. In two patients with left-sided AP, the ablation was performed via a patent foramen ovale.
A total of 47 APs were present, left sided in 45% (21/47) of cases (15 lateral, one anterior, three posteroseptal, and two posterolateral) and right sided in 55% (26/47; one anterior, three anterolateral, one posterolateral, three lateral, five para-Hisian, 12 posteroseptal, and one anteroseptal). Ablation without the use of fluoroscopy was successfully performed in every patient (33 with RF and in 11 with cryoenergy). No complication occurred. At a mean follow-up of 16.0 ± 11.7 months, we observed seven recurrences, three of them successfully re-ablated without fluoroscopy. In one case cryoablation of a para-Hisian AP was ineffective in the long term.
Three-dimensional EAM allowed a safe and effective fluoroless AP ablation procedure in a pediatric population both with RF and cryoenergy.
考虑到儿科患者的敏感性及其较长的预期寿命,小儿心律失常的荧光镜导管消融术会使患者面临辐射的潜在风险。我们评估了在CARTO3电解剖标测(EAM)系统引导下,使用冷冻能量和射频(RF)能量进行旁路(AP)消融的可行性、安全性和有效性,以避免儿科患者接受X射线照射。
我们纳入了44例患者(平均年龄:13.1±3.3岁);44例中有9例表现为隐匿性AP。对每例患者均采用经股静脉直接右心房入路或经股动脉逆行入路进行电生理研究,并进行三维EAM重建,以到达二尖瓣环。对于2例左侧AP患者,通过卵圆孔未闭进行消融。
共有47条AP,45%(21/47)的病例位于左侧(15条外侧、1条前侧、3条后间隔和2条后外侧),55%(26/47)位于右侧(1条前侧、3条前外侧、1条后外侧、3条外侧、5条希氏束旁、12条后间隔和1条前间隔)。所有患者均成功进行了无荧光镜引导的消融(33例使用RF,11例使用冷冻能量)。未发生并发症。平均随访16.0±11.7个月时,我们观察到7例复发,其中3例在无荧光镜引导下成功再次消融。1例希氏束旁AP的冷冻消融长期无效。
三维EAM使儿科患者使用RF和冷冻能量进行安全有效的无荧光镜AP消融手术成为可能。