Wada Hajime, Saito Masato, Kamada Kyousuke
Hajime Wada, Masato Saito, Kyousuke Kamada, Department of Neurosurgery, Asahikawa Medical University, Asahikawa, Hokkaido 0788510, Japan.
World J Radiol. 2015 Feb 28;7(2):45-51. doi: 10.4329/wjr.v7.i2.45.
To evaluate the changes of intracranial blood flow after carotid artery stenting (CAS), using the flow assessment application "Flow-Insight", which was developed in our department.
Twenty patients treated by CAS participated in this study. We analyzed the change in concentration of the contrast media at the anterior-posterior and profile view image with the flow assessment application "Flow-Insight". And we compared the results with N-isopropyl-p-[123I] iodoamphetamine-single-photon emission computed tomography (IMP SPECT) performed before and after the treatment.
From this study, 200% of the parameter "blood flow" change in the post/pre-treatment is suggested as the critical line of the hyperperfusion syndrome arise. Although the observed blood flow increase in the digital subtraction angiography system did not strongly correlate with the rate of increase of SPECT, the "Flow-Insight" reflected the rate of change of the vessels well. However, for patients with reduced reserve blood flow before CAS, a highly elevated site was in agreement with the site analysis results.
We concluded that the cerebral angiography flow assessment application was able to more finely reveal hyperperfusion regions in the brain after CAS compared to SPECT.
使用我们科室开发的血流评估应用程序“Flow-Insight”评估颈动脉支架置入术（CAS）后颅内血流的变化。
20例接受CAS治疗的患者参与了本研究。我们使用血流评估应用程序“Flow-Insight”分析前后位和侧位图像上造影剂浓度的变化。并且我们将结果与治疗前后进行的N-异丙基-p-[123I] 碘安非他明单光子发射计算机断层扫描（IMP SPECT）进行比较。
从本研究来看，治疗后与治疗前“血流”参数变化200%被认为是发生高灌注综合征的临界线。尽管在数字减影血管造影系统中观察到的血流增加与SPECT的增加率没有很强的相关性，但“Flow-Insight”能很好地反映血管的变化率。然而，对于CAS前储备血流减少的患者，高度升高的部位与部位分析结果一致。
我们得出结论，与SPECT相比，脑血管造影血流评估应用程序能够更精细地显示CAS后大脑中的高灌注区域。
