Tsubota Yu, Sueoka Noriko, Yamamoto Daigo
Dept. of Breast Surgery, Kansai Medical University Takii Hospital.
Gan To Kagaku Ryoho. 2014 Nov;41(12):1954-6.
A 60-year-old woman with left breast cancer underwent partial mastectomy and sentinel lymph node biopsy. Pathological examination revealed an invasive ductal carcinoma that was ER (+), PgR (-), HER2 (-), and node positive (1/1). She received adjuvant chemotherapy with doxorubicin and cyclophosphamide (AC), followed by weekly paclitaxel (PTX). After receiving radiation therapy, she was administered an aromatase inhibitor for 5 years. Six months after completion of therapy, she found a hard lymph node in the left infraclavicular area. Fine needle aspiration cytology of the lymph node indicated metastatic breast cancer. Fulvestrant was administered but disease progression was observed after 3 months. Systemic chemotherapy with PTX and bevacizumab (Bev) was begun. After 3 cycles of chemotherapy, computed tomography (CT) scan revealed a complete response (CR). After 6 cycles of chemotherapy, the CR has been maintained.
一名60岁的左乳腺癌女性接受了部分乳房切除术和前哨淋巴结活检。病理检查显示为浸润性导管癌,雌激素受体(ER)阳性、孕激素受体(PgR)阴性、人表皮生长因子受体2(HER2)阴性,且淋巴结阳性(1/1)。她接受了阿霉素和环磷酰胺(AC)辅助化疗,随后接受每周一次的紫杉醇(PTX)治疗。接受放射治疗后,她接受了5年的芳香化酶抑制剂治疗。治疗结束6个月后,她在左锁骨下区域发现一个硬淋巴结。淋巴结细针穿刺细胞学检查提示为转移性乳腺癌。给予氟维司群治疗,但3个月后观察到疾病进展。开始使用PTX和贝伐单抗(Bev)进行全身化疗。化疗3个周期后,计算机断层扫描(CT)显示完全缓解(CR)。化疗6个周期后,CR一直维持。