Nishiyama Mitsuo, Yoshino Shigefumi, Matsui Hiroto, Sakamoto Kazuhiko, Suzuki Nobuaki, Tamesa Takao, Takeda Shigeru, Ueno Tomio, Hazama Shouichi, Oka Masaaki
Dept. of Digestive Surgery and Surgical Oncology, Yamaguchi University Graduate School of Medicine.
Gan To Kagaku Ryoho. 2014 Nov;41(12):2352-4.
The use of hepatectomy for the treatment of liver metastasis from gastric cancer has been controversial. We report a case of metachronous liver metastasis from gastric cancer, which we successfully treated with hepatectomy. A 59-year-old man underwent laparoscopy-assisted total gastrectomy with D1 plus lymphadenectomy for gastric cancer. The histopathological findings revealed that the tumor was a well-differentiated tubular adenocarcinoma, T2(MP), N1(#1 2/3), M0, fStage II, according to the 14th edition of the Japanese Classification of Gastric Carcinoma. TS-1 was administered as adjuvant chemo- therapy for 1 year after the operation. About 5 years after the gastrectomy, a recurrent tumor was detected in S5/8-7 of the liver. Although chemotherapy with TS-1 plus Lentinan was administered, the liver tumor increased in size. Percutaneous transhepatic portal embolization was performed to improve liver function followed by resection of the right lobe of the liver. Paclitaxel plus doxifluridine (5'-DFUR) was administered for 6 months as adjuvant chemotherapy. No recurrence was observed for 17 months after hepatectomy.
