Fujimoto Takuya, Abe Toshihiro, Okabe Yu, Johshima Kazutaka, Fukuyama Keita, Noda Tomohiro, Shimoike Norihiro, Maekawa Hisatsugu, Tada Seiichiro, Iwata Teruo, Yoshimoto Yasunori, Fujikawa Takahisa, Tanaka Akira
Dept. of Surgery, Kokura Memorial Hospital.
Gan To Kagaku Ryoho. 2014 Nov;41(12):2462-4.
We report a case of adenocarcinoma occurring in the bladder mucosa 6 years after a surgical operation for colovesical fistula due to colonic diverticulitis of the sigmoid colon. The patient was a 76-year-old woman who had undergone a sigmoidectomy and ligation of the colovesical fistula at the age of 70 years. She presented with a complaint of gross hematuria. Cystoscopy and computed tomography revealed bladder cancer at the site of the original colovesical fistula surgery. She underwent transurethral resection of the bladder tumor. Histopathological findings revealed intestinal adenocarcinoma in the urinary bladder. A radical partial cystectomy was subsequently performed because of a positive and involved margin. This tumor may have originated from the bladder mucosa and then replaced by intestinal metaplastic cells that originated from the same initiating event.
我们报告一例因乙状结肠憩室炎导致结肠膀胱瘘手术6年后膀胱黏膜发生腺癌的病例。患者为一名76岁女性，70岁时接受了乙状结肠切除术及结肠膀胱瘘结扎术。她因肉眼血尿就诊。膀胱镜检查和计算机断层扫描显示，原结肠膀胱瘘手术部位存在膀胱癌。她接受了经尿道膀胱肿瘤切除术。组织病理学检查结果显示膀胱内为肠腺癌。由于切缘阳性且受累，随后进行了根治性部分膀胱切除术。该肿瘤可能起源于膀胱黏膜，然后被源自同一起始事件的肠化生细胞所取代。
