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压力性溃疡的治疗:美国医师学院的临床实践指南。

Treatment of pressure ulcers: a clinical practice guideline from the American College of Physicians.

出版信息

Ann Intern Med. 2015 Mar 3;162(5):370-9. doi: 10.7326/M14-1568.

Abstract

DESCRIPTION

The American College of Physicians (ACP) developed this guideline to present the evidence and provide clinical recommendations based on the comparative effectiveness of treatments of pressure ulcers.

METHODS

This guideline is based on published literature on this topic that was identified by using MEDLINE, EMBASE, CINAHL, EBM Reviews, the Cochrane Central Register of Controlled Trials, the Cochrane Database of Systematic Reviews, the Database of Abstracts of Reviews of Effects, and the Health Technology Assessment database through February 2014. Searches were limited to English-language publications. The outcomes evaluated for this guideline include complete wound healing, wound size (surface area, volume, and depth) reduction, pain, prevention of sepsis, prevention of osteomyelitis, recurrence rate, and harms of treatment (including but not limited to pain, dermatologic complications, bleeding, and infection). This guideline grades the quality of evidence and strength of recommendations by using ACP's clinical practice guidelines grading system. The target audience for this guideline includes all clinicians, and the target patient population is patients with pressure ulcers.

RECOMMENDATION 1: ACP recommends that clinicians use protein or amino acid supplementation in patients with pressure ulcers to reduce wound size. (Grade: weak recommendation, low-quality evidence).

RECOMMENDATION 2: ACP recommends that clinicians use hydrocolloid or foam dressings in patients with pressure ulcers to reduce wound size. (Grade: weak recommendation, low-quality evidence).

RECOMMENDATION 3: ACP recommends that clinicians use electrical stimulation as adjunctive therapy in patients with pressure ulcers to accelerate wound healing. (Grade: weak recommendation, moderate-quality evidence).

摘要

描述

美国医师学会(ACP)制定本指南,旨在评估治疗压疮的各种疗法的相对有效性,并提供临床推荐意见。

方法

本指南以发表的相关文献为基础,主要检索了 MEDLINE、EMBASE、CINAHL、EBM Reviews、Cochrane 中心对照试验注册库、Cochrane 系统评价数据库、疗效评价文摘数据库以及卫生技术评估数据库中截至 2014 年 2 月的相关资料。检索语言限定为英文。本指南评估的结局指标包括完全愈合、创面面积(表面积、体积和深度)缩小、疼痛、预防败血症、预防骨髓炎、复发率以及治疗相关危害(包括但不限于疼痛、皮肤并发症、出血和感染)。本指南采用 ACP 临床实践指南分级系统对证据质量和推荐强度进行分级。本指南的目标受众为所有临床医生,目标患者人群为压疮患者。

推荐意见 1:ACP 建议对压疮患者使用蛋白质或氨基酸补充剂以缩小创面面积。(弱推荐,低质量证据)

推荐意见 2:ACP 建议对压疮患者使用水胶体或泡沫敷料以缩小创面面积。(弱推荐,低质量证据)

推荐意见 3:ACP 建议对压疮患者采用电刺激作为辅助治疗以加速创面愈合。(弱推荐,中等质量证据)

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