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[科贾埃利省德林切微生物实验室对育龄期女性患者进行弓形虫筛查结果的回顾性评估]

[Retrospective evaluation of the results of female patients of childbearing age at a microbiology laboratory for screening Toxoplasma gondii in Kocaeli Derince].

作者信息

Yazıcı Vesile, Kale Ahmet, Malatyalı Erdoğan, Ertabaklar Hatice

机构信息

Kocaeli Derince Eğitim ve Araştırma Hastanesi, Tıbbi Mikrobiyoloji Anabilim Dalı, Kocaeli, Türkiye.

出版信息

Turkiye Parazitol Derg. 2014 Dec;38(4):223-7. doi: 10.5152/tpd.2014.3519.

Abstract

OBJECTIVE

The aim of the previous study was to retrospectively analyze the seropositive rate of Toxoplasma among women of childbearing age who were suspected to have toxoplasmosis at the Microbiology Laboratory of Kocaeli Derince Education and Research Hospital.

METHODS

The presence of Toxoplasma antibodies (IgM, IgG) with Axsym commercial ELISA kits between January 2009 and February 2011 and the presence of Toxoplasma antibodies (IgM, IgG) with Architect commercial ELISA kit between February 2011 and June 2012 were investigated in a total of 943 sera from women included in the study.

RESULTS

The seropositive rate of anti-Toxoplasma IgG and IgM in the study was 28.5% (N=741), 0.9% (N=898), respectively. Additionally, 10 samples (1.3%) were considered as border-line for IgG antibodies and 4 samples (0.4%) for IgM antibodies against T. gondii.

CONCLUSION

In general, 70.2% of women in the study were seronegative for anti-Toxoplasma IgG antibodies; it can be concluded that most of them were sensitive to a newly acquired infection, and that their babies were at risk of congenital toxoplasmosis in case of a possible pregnancy. In conclusion, the present study suggested that toxoplasmosis was still an emerging public health problem in study area, and particularly, women of reproductive age should be warned and informed about toxoplasmosis.

摘要

目的

先前研究的目的是回顾性分析在科贾埃利代林塞教育与研究医院微生物实验室疑似患有弓形虫病的育龄妇女中弓形虫的血清阳性率。

方法

在2009年1月至2011年2月期间,使用Axsym商用酶联免疫吸附测定试剂盒检测了纳入研究的女性的943份血清中弓形虫抗体(IgM、IgG)的存在情况;在2011年2月至2012年6月期间,使用Architect商用酶联免疫吸附测定试剂盒检测了这些血清中弓形虫抗体(IgM、IgG)的存在情况。

结果

该研究中抗弓形虫IgG和IgM的血清阳性率分别为28.5%(N = 741)、0.9%(N = 898)。此外,10份样本(1.3%)的IgG抗体被视为临界值,4份样本(0.4%)的抗弓形虫IgM抗体被视为临界值。

结论

总体而言,该研究中70.2%的女性抗弓形虫IgG抗体血清学阴性;可以得出结论,她们中的大多数对新获得的感染敏感,并且如果可能怀孕,其婴儿有患先天性弓形虫病的风险。总之,本研究表明弓形虫病在研究区域仍然是一个新出现的公共卫生问题,特别是,应该对育龄妇女进行弓形虫病的警告和宣传。

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