Fernández Óscar
Unidad de Gestión Clínica de Neurociencias, Servicio de Neurología, Hospitales Universitarios Regional y Virgen de la Victoria de Málaga, Málaga, España; Instituto de Investigación en Biomedicina de Málaga (IBIMA), Universidad de Málaga, Málaga, España.
Med Clin (Barc). 2014 Dec;143 Suppl 3:44-7. doi: 10.1016/S0025-7753(15)30010-5.
Multiple sclerosis occurs in genetically susceptible individuals, in whom an unknown environmental factor triggers an immune response, giving rise to a chronic and disabling autoimmune disease. Currently, significant progress is being made in our knowledge of the frequency and distribution of multiple sclerosis and its risk factors, genetics, pathology, pathogenesis, diagnostic and prognostic markers, and treatment. This has radically changed patients' and clinicians' expectations of multiple sclerosis and has raised hope that there will soon be a way to control the disease.
多发性硬化症发生在具有遗传易感性的个体中，在这些个体中，一种未知的环境因素引发免疫反应，从而导致一种慢性致残性自身免疫性疾病。目前，我们在多发性硬化症的发病率、分布情况及其危险因素、遗传学、病理学、发病机制、诊断和预后标志物以及治疗方面的认识正在取得重大进展。这从根本上改变了患者和临床医生对多发性硬化症的期望，并燃起了很快就能找到控制该病方法的希望。
