Rafferty P
Department of Respiratory Medicine, Western Infirmary, Glasgow, Scotland.
Ann Allergy. 1989 Nov;63(5):389-91.
Until the appearance of nonsedating antihistamines such as terfenadine and astemizole, clinical studies of H1 antagonists in the treatment of asthma yielded disappointing results. The author reviews recent European studies that demonstrate terfenadine's effectiveness in reducing symptoms and improving bronchodilation in patients with mild atopic asthma.
在非镇静性抗组胺药如特非那定和阿司咪唑出现之前,H1拮抗剂治疗哮喘的临床研究结果令人失望。作者回顾了近期欧洲的研究,这些研究表明特非那定在减轻轻度特应性哮喘患者症状和改善支气管扩张方面有效。