Heiniger Louise, Price Melanie A, Charles Margaret, Butow Phyllis N
Psycho-Oncology Cooperative Research Group (PoCoG), University of Sydney, Level 6 North, Chris O'Brien Lifehouse (C39Z), NSW, 2006, Sydney, Australia.
School of Psychology, University of Sydney, NSW, 2006, Sydney, Australia.
J Genet Couns. 2015 Dec;24(6):890-907. doi: 10.1007/s10897-015-9824-x. Epub 2015 Mar 5.
Little is known about the process of psychosocial adaptation to familial risk in tested and untested individuals at increased familial risk of cancer. This paper presents findings from a qualitative study of 36 women participating in the Kathleen Cuningham Consortium for Research into Familial Breast cancer (kConFab) Psychosocial study. Facilitators and challenges in psychosocial adaptation were identified through semi-structured interviews. The women, who were either tested (carriers or non-carriers of breast cancer susceptibility mutations) or untested (ineligible for testing or eligible but delayed or declined testing), described personal, support network and healthcare characteristics that impacted on the adaptation process. Challenges in one domain could be overcome by facilitators in other domains and key differences relating to whether women had undergone testing, or not, were identified. Tested and untested women with an increased familial risk of breast cancer may benefit from support tailored to their mutation testing status in order to enhance adaptation.
对于处于癌症家族风险增加状态的已检测和未检测个体，其心理社会适应过程鲜为人知。本文呈现了一项针对36名参与凯瑟琳·坎宁安家族性乳腺癌研究联盟（kConFab）心理社会研究的女性的定性研究结果。通过半结构化访谈确定了心理社会适应过程中的促进因素和挑战。这些女性要么已接受检测（乳腺癌易感基因突变携带者或非携带者），要么未接受检测（不符合检测条件、符合条件但延迟检测或拒绝检测），她们描述了影响适应过程的个人、支持网络和医疗保健特征。一个领域的挑战可以通过其他领域的促进因素来克服，并且确定了与女性是否接受检测相关的关键差异。乳腺癌家族风险增加的已检测和未检测女性可能会受益于根据其突变检测状态量身定制的支持，以增强适应能力。
