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童年逆境与成人期慢性疼痛:日本世界心理健康调查结果

Childhood adversities and adult-onset chronic pain: Results from the World Mental Health Survey, Japan.

作者信息

Stickley A, Koyanagi A, Kawakami N

机构信息

Department of Human Ecology, Graduate School of Medicine, The University of Tokyo, Japan.

Stockholm Centre on Health of Societies in Transition (SCOHOST), Södertörn University, Huddinge, Sweden.

出版信息

Eur J Pain. 2015 Nov;19(10):1418-27. doi: 10.1002/ejp.672. Epub 2015 Mar 2.

Abstract

BACKGROUND

Childhood adversities (CAs) have been associated with adult-onset chronic pain. However, to date, most single country studies on this association have been undertaken in Western countries. This study examined the association in Japan where information is scarce.

METHODS

Data were drawn from the World Mental Health Survey Japan, a population-based cross-sectional survey undertaken in 11 areas of Japan in 2002-2006. We analyzed data from adults aged ≥20 years who provided information on CAs occurring before age 18 years and chronic pain (n = 1740). Cox proportional hazard models were used to estimate the risk for different forms of adult-onset chronic pain (arthritis/rheumatism, neck/back pain, headache and any pain) as a function of the presence of 11 different types of CA and the number of CAs.

RESULTS

In the adjusted models, significant associations were observed between: physical abuse and neck/back pain (HR 2.55) and any pain (HR 1.88); sexual abuse and any pain (HR 2.84). Significant dose-dependent relationships were also observed between a greater number of CAs and some adult-onset chronic pain conditions (neck/back and any pain).

CONCLUSIONS

The results of this study suggest that in Japan, some forms of CA may be associated with certain types of adult-onset chronic pain, in particular neck/back pain.

摘要

背景

童年逆境(CAs)与成人期慢性疼痛有关。然而,迄今为止,大多数关于这种关联的单一国家研究都是在西方国家进行的。本研究在相关信息稀缺的日本对这种关联进行了调查。

方法

数据来自日本世界心理健康调查,这是一项于2002年至2006年在日本11个地区开展的基于人群的横断面调查。我们分析了年龄≥20岁的成年人的数据,这些成年人提供了18岁之前发生的童年逆境和慢性疼痛的相关信息(n = 1740)。使用Cox比例风险模型来估计11种不同类型童年逆境的存在情况及童年逆境数量与不同形式成人期慢性疼痛(关节炎/风湿病、颈/背痛、头痛及任何疼痛)之间的风险关系。

结果

在调整后的模型中,观察到以下显著关联:身体虐待与颈/背痛(风险比[HR] 2.55)及任何疼痛(HR 1.88);性虐待与任何疼痛(HR 2.84)。在更多童年逆境与一些成人期慢性疼痛状况(颈/背痛及任何疼痛)之间也观察到显著的剂量依赖关系。

结论

本研究结果表明,在日本,某些形式的童年逆境可能与某些类型的成人期慢性疼痛有关,尤其是颈/背痛。

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