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全髋关节翻修术:与再次翻修手术相关的因素。

Revision total hip arthoplasty: factors associated with re-revision surgery.

作者信息

Khatod Monti, Cafri Guy, Inacio Maria C S, Schepps Alan L, Paxton Elizabeth W, Bini Stefano A

机构信息

Department of Orthopaedic Surgery, Southern California Permanente Medical Group, 6041 Cadillac Avenue, Los Angeles, CA 90034. E-mail address for M. Khatod:

Surgical Outcomes and Analysis, Kaiser Permanente, 8954 Rio San Diego Drive, Suite 406, San Diego, CA 92108.

出版信息

J Bone Joint Surg Am. 2015 Mar 4;97(5):359-66. doi: 10.2106/JBJS.N.00073.

Abstract

BACKGROUND

The survivorship of implants after revision total hip arthroplasty and risk factors associated with re-revision are not well defined. We evaluated the re-revision rate with use of the institutional total joint replacement registry. The purpose of this study was to determine patient, implant, and surgeon factors associated with re-revision total hip arthroplasty.

METHODS

A retrospective cohort study was conducted. The total joint replacement registry was used to identify patients who had undergone revision total hip arthroplasty for aseptic reasons from April 1, 2001, to December 31, 2010. The end point of interest was re-revision total hip arthroplasty. Risk factors evaluated for re-revision total hip arthroplasty included: patient risk factors (age, sex, body mass index, race, and general health status), implant risk factors (fixation type, bearing surface, femoral head size, and component replacement), and surgeon risk factors (volume and experience). A multivariable Cox proportional hazards model was used.

RESULTS

Six hundred and twenty-nine revision total hip arthroplasties with sixty-three (10%) re-revisions were evaluated. The mean cohort age (and standard deviation) was 57.0 ± 12.4 years, the mean body mass index (and standard deviation) was 29.5 ± 6.1 kg/m(2), and most of the patients were women (64.5%) and white (81.9%) and had an American Society of Anesthesiologists score of <3 (52.9%). The five-year implant survival after revision total hip arthroplasty was 86.8% (95% confidence interval, 83.57% to 90.25%). In adjusted models, age, total number of revision surgical procedures performed by the surgeon, fixation, and bearing surface were associated with the risk of re-revision. For every ten-year increase in patient age, the hazard ratio for re-revision decreases by a factor of 0.72 (95% confidence interval, 0.58 to 0.90). For every five revision surgical procedures performed by a surgeon, the risk of revision decreases by a factor of 0.93 (95% confidence interval, 0.86 to 0.99). At the time of revision, a new or retained cemented femoral implant or all-cemented hip implant increases the risk of revision by a factor of 3.19 (95% confidence interval, 1.22 to 8.38) relative to a retained or new uncemented hip implant. A ceramic on a highly cross-linked polyethylene bearing articulation decreases the hazard relative to metal on highly cross-linked polyethylene by a factor of 0.32 (95% confidence interval, 0.11 to 0.95). Metal on constrained bearing increases the hazard relative to metal on highly cross-linked polyethylene by a factor of 3.32 (95% confidence interval, 1.16 to 9.48).

CONCLUSIONS

When evaluating patient, implant, and surgical factors at the time of revision total hip arthroplasty, age, surgeon experience, implant fixation, and bearing surfaces had significant impacts on the risk of re-revision.

摘要

背景

翻修全髋关节置换术后假体的生存率以及与再次翻修相关的危险因素尚未明确界定。我们利用机构全关节置换登记系统评估了再次翻修率。本研究的目的是确定与翻修全髋关节置换术相关的患者、假体及外科医生因素。

方法

进行了一项回顾性队列研究。利用全关节置换登记系统确定2001年4月1日至2010年12月31日期间因无菌性原因接受翻修全髋关节置换术的患者。感兴趣的终点是再次翻修全髋关节置换术。评估翻修全髋关节置换术的危险因素包括:患者危险因素(年龄、性别、体重指数、种族和一般健康状况)、假体危险因素(固定类型、关节面、股骨头大小和组件置换)以及外科医生危险因素(手术量和经验)。使用多变量Cox比例风险模型。

结果

对629例翻修全髋关节置换术进行了评估,其中63例(10%)再次翻修。队列的平均年龄(及标准差)为57.0±12.4岁,平均体重指数(及标准差)为29.5±6.1kg/m²,大多数患者为女性(64.5%)、白人(81.9%),美国麻醉医师协会评分<3分(52.9%)。翻修全髋关节置换术后五年的假体生存率为86.8%(95%置信区间,83.57%至90.25%)。在调整模型中,年龄、外科医生进行的翻修手术总数、固定方式和关节面与再次翻修风险相关。患者年龄每增加十岁,再次翻修的风险比降低0.72倍(95%置信区间,0.58至0.90)。外科医生每进行五次翻修手术,再次翻修的风险降低0.93倍(95%置信区间,0.86至0.99)。在翻修时,与保留或新的非骨水泥型髋关节假体相比,新的或保留的骨水泥型股骨假体或全骨水泥型髋关节假体使再次翻修的风险增加3.19倍(95%置信区间,1.22至8.38)。与金属对高交联聚乙烯关节面相比,陶瓷对高交联聚乙烯关节面使风险比降低0.32倍(95%置信区间,0.11至0.95)。与金属对高交联聚乙烯关节面相比,金属对限制性关节面使风险比增加3.32倍(95%置信区间,1.16至9.48)。

结论

在评估翻修全髋关节置换术时的患者、假体和手术因素时,年龄、外科医生经验、假体固定方式和关节面对再次翻修风险有显著影响。

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